U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 71 - 80 of 587 results

Hygromycin B is a water-soluble antibiotic purified from the bacterium Streptomyces hydroscopicus.It kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. It has been reported to interfere with translocation and to cause mistranslation at the 70S ribosome.Hygromycin B is used as a selective agent in molecular genetics experiments on a wide variety of eukaryotic and prokaryotic species. Under the trade name Hygromix, Hygromycin B is used in chickens as an aid in the control of infections of the following intestinal parasites: large roundworms (Ascaris galli), cecal worms (Heterakis gallinae) and capillary worms (Capillaria obsignata) and in Swine as an aid in the control of infections of the following intestinal parasites: large roundworms (Ascaris suis), nodular worms (Oesophagostomum dentatum) and whipworms (Trichuris suis).
Cianidanol is an antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms. One of the polyphenols present in green tea, (+)-catechin (Cianidanol), has been studied for its effects on animal models of hepatitis, as well as in human clinical studies. Pure (+)-catechin (also known as (+)- cyanidanol-3 – trade name Catergen) has been used to treat hepatitis since 1976. This compound has been shown to be an efficient immune stimulator, promoting activation of macrophages, cytotoxic-T-lymphocytes, and natural killer cells in mice. Several clinical studies demonstrate the effectiveness of (+)-catechin in the treatment of viral hepatitis. Pure (+)-catechin has been found to cause hemolysis in some patients, possibly by the promotion of antibody formation against (+)-catechin, which might cross-react with red blood cells. However, there are no reports in the literature of green tea, green tea extracts, or green tea polyphenols causing this side-effect.
Status:
Possibly Marketed Outside US
Source:
part348
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

2-(L-MENTHOXY)ETHANOL is used as a food additive and it has been described as bland and odorless with a minty aroma. There are currently no safety concerns regarding the use of this compound (latest evaluation 2008). It belongs to the class of organic compounds known as menthane monoterpenoids.
Status:
Possibly Marketed Outside US
First approved in 2011
Source:
SODIUM SULFACETAMIDE by Acella Pharmaceuticals, LLC
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US
Source:
Isaknox Tervina Lumiere White by Lg Household & Health Care Ltd.
Source URL:
First approved in 2011
Source:
ISAKNOX TERVINA LUMIERE WHITE by LG Household and Healthcare, Inc.
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Methyl undecenoyl leucinate is an active ingredient in whitening creams. This compound belongs to the class of organic compounds known as leucine and derivatives. Methyl undecenoyl leucinate inhibits the -MSH-induced adenylate cyclase (AC) and protein kinase A (PKA) activation, down-regulates melanogenic gene expressions such as MITF, tyrosinase, TRP-1 and TRP-2 (DCT) and finally suppresses melanin synthesis. The recommended concentration is between 2-4% and tests have shown neither cytotoxic effects nor irritation or sensitization reactions in healthy volunteers.