Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H33NO3 |
| Molecular Weight | 311.4595 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC(=O)[C@H](CC(C)C)NC(=O)CCCCCCCCC=C
InChI
InChIKey=ICMAWHHKHYZNDA-INIZCTEOSA-N
InChI=1S/C18H33NO3/c1-5-6-7-8-9-10-11-12-13-17(20)19-16(14-15(2)3)18(21)22-4/h5,15-16H,1,6-14H2,2-4H3,(H,19,20)/t16-/m0/s1
| Molecular Formula | C18H33NO3 |
| Molecular Weight | 311.4595 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Methyl undecenoyl leucinate is an active ingredient in whitening creams. This compound belongs to the class of organic compounds known as leucine and derivatives. Methyl undecenoyl leucinate inhibits the -MSH-induced adenylate cyclase (AC) and protein kinase A (PKA) activation, down-regulates melanogenic gene expressions such as MITF, tyrosinase, TRP-1 and TRP-2 (DCT) and finally suppresses melanin synthesis. The recommended concentration is between 2-4% and tests have shown neither cytotoxic effects nor irritation or sensitization reactions in healthy volunteers.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 20:02:04 GMT 2023
by
admin
on
Fri Dec 15 20:02:04 GMT 2023
|
| Record UNII |
D7PH6N3IEI
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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D7PH6N3IEI
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D7PH6N3IEI
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56843908
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DB11272
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1427065
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admin on Fri Dec 15 20:02:04 GMT 2023 , Edited by admin on Fri Dec 15 20:02:04 GMT 2023
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1246371-29-8
Created by
admin on Fri Dec 15 20:02:04 GMT 2023 , Edited by admin on Fri Dec 15 20:02:04 GMT 2023
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ACTIVE MOIETY |
