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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H33NO3
Molecular Weight 311.4595
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYL UNDECENOYL LEUCINATE

SMILES

COC(=O)[C@H](CC(C)C)NC(=O)CCCCCCCCC=C

InChI

InChIKey=ICMAWHHKHYZNDA-INIZCTEOSA-N
InChI=1S/C18H33NO3/c1-5-6-7-8-9-10-11-12-13-17(20)19-16(14-15(2)3)18(21)22-4/h5,15-16H,1,6-14H2,2-4H3,(H,19,20)/t16-/m0/s1

HIDE SMILES / InChI
Methyl undecenoyl leucinate is an active ingredient in whitening creams. This compound belongs to the class of organic compounds known as leucine and derivatives. Methyl undecenoyl leucinate inhibits the -MSH-induced adenylate cyclase (AC) and protein kinase A (PKA) activation, down-regulates melanogenic gene expressions such as MITF, tyrosinase, TRP-1 and TRP-2 (DCT) and finally suppresses melanin synthesis. The recommended concentration is between 2-4% and tests have shown neither cytotoxic effects nor irritation or sensitization reactions in healthy volunteers.

Approval Year

Name Type Language
METHYL UNDECENOYL LEUCINATE
INCI  
INCI  
Official Name English
L-LEUCINE, N-(1-OXO-10-UNDECEN-1-YL)-, METHYL ESTER
Common Name English
METHYL UNDECENOYL LEUCINATE [INCI]
Common Name English
Code System Code Type Description
FDA UNII
D7PH6N3IEI
Created by admin on Fri Dec 15 20:02:04 GMT 2023 , Edited by admin on Fri Dec 15 20:02:04 GMT 2023
PRIMARY
DAILYMED
D7PH6N3IEI
Created by admin on Fri Dec 15 20:02:04 GMT 2023 , Edited by admin on Fri Dec 15 20:02:04 GMT 2023
PRIMARY
PUBCHEM
56843908
Created by admin on Fri Dec 15 20:02:04 GMT 2023 , Edited by admin on Fri Dec 15 20:02:04 GMT 2023
PRIMARY
DRUG BANK
DB11272
Created by admin on Fri Dec 15 20:02:04 GMT 2023 , Edited by admin on Fri Dec 15 20:02:04 GMT 2023
PRIMARY
RXCUI
1427065
Created by admin on Fri Dec 15 20:02:04 GMT 2023 , Edited by admin on Fri Dec 15 20:02:04 GMT 2023
PRIMARY RxNorm
CAS
1246371-29-8
Created by admin on Fri Dec 15 20:02:04 GMT 2023 , Edited by admin on Fri Dec 15 20:02:04 GMT 2023
PRIMARY