U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

Showing 51 - 60 of 239 results

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US
First approved in 2007
Source:
SEMDURAMICIN 150 by Phibro Saude Animal Internacional Ltda
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Semduramicin is an ionophore coccidiostat used in the poultry industry as a feed additive. Semduramicin is marketed under the brand name Aviax among others, indicated for the prevention of coccidiosis in poultry, caused by Eimeria tenella, E. acervulina, E. maxima, E. brunetti, E. necatrix, and E. mitis.
Status:
Possibly Marketed Outside US
Source:
NCT02587117: Phase 4 Interventional Completed Oral Lichen Planus
(2013)
Source URL:
First approved in 2007
Source:
Corvite Free by Vertical Pharmaceuticals, LLC
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Lycopene is the fat-soluble pigment that gives tomatoes, watermelon, pink grapefruit, and other foods their red color. Bioavailability of lycopene is enhanced in the presence of lipids and thermal processing. Lycopene accounts for about 50% of the carotenoids found in human serum and is among the major carotenoids present in human milk. The antioxidant activity of lycopene and its use in cancer prevention and cardiovascular disease have been widely documented. The scientific literature documents some adverse reactions, such as diarrhea, dyspepsia, gas, nausea, and vomiting. One trial documented a cancer-related hemorrhage in a patient taking lycopene, although causality is unclear. Lycopene interacts with some cancer chemotherapy agents, as well as with ciprofloxacin and olestra.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

Panthenyl ethyl ether is used in cosmetic as an antistatic and hair conditioning. However, it was found that in patients with psoriasis panthenyl ethyl ether could cause allergic contact dermatitis.
Status:
Possibly Marketed Outside US
Source:
Tinosorb M by Orfagen
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Bisoctrizole (Tinosorb M) is a hybrid type sun blocking agent acting as both chemical and physical sunscreen. Bisoctrizole is a hybrid UV absorber, the only organic UV filter produced and microfine organic particles (< 200 nm), like microfine zinc oxide and titanium dioxide. Where other organic UV absorbers need to be dissolved in either the oil or water phase, bisoctrizole dissolves poorly in both. It covers both UVA and UVB range. Furthermore, it does not degrade under sunlight and is not significantly absorbed into the skin. It appear highly compatible with many other common sun blocking agents. Overall, it appears to have a good safety profile, even though current safety data are insufficient and long-term human safety studies are lacking. Unlike some other organic sunscreen actives, it shows no estrogenic effects in vitro. Bisoctrizole is not approved by the U.S. Food and Drug Administration (FDA), but is approved in the EU and other parts of the world. Bisoctrizole is highly stable and also has a stabilizing effect on other UV absorbers, particularly the UVB blocker octyl methoxycinnamate (octinoxate). Bisoctrizole appears to be relatively non-toxic and rarely causes skin irritation. As with many synthetic chemicals, it is unclear whether bisoctrizole may produce low-level skin damage or systemic effects with long-term use. Considering that bisoctrizole is stable, poorly soluble and minimally absorbed by the skin, the risks appear to be low. Still, more research is on bisoctrizole safety is needed.
Status:
Possibly Marketed Outside US
Source:
ProCoMycin by Physicians Science & Nature Inc.
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Erythorbic acid, an epimer of L-ascorbic acid, is used in the United States as a food additive. It was studied, that erythorbic acid enhanced of iron absorption and could play a major role in enhancing iron bioavailability from mixed diets that include foods preserved with erythorbic acid. In addition, was investigated if the erythorbic acid could influence on the metabolism of vitamin C in young women, and obtained results showed, that prolonged ingestion of erythorbic acid had no effect on vitamin C uptake or clearance from the body.
Status:
Possibly Marketed Outside US
Source:
CFR:21 CFR 310.201
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Gentisic acid is an active metabolite of salicylic acid degradation, which possesses a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties. The antioxidant activity and radioprotective properties of gentisic acid are exerted by its phenoxyl group. It is also used in cosmetics as a skin-whitening agent for the treatment of skin pigmentary disorders by influencing the synthesis of melanin through inhibition of melanosomal tyrosinase activity Gentisic acid is also a biomarker of Renal Cell Carcinoma.