U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C6H8O6
Molecular Weight 176.1241
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ERYTHORBIC ACID

SMILES

[H][C@@]1(OC(=O)C(O)=C1O)[C@H](O)CO

InChI

InChIKey=CIWBSHSKHKDKBQ-DUZGATOHSA-N
InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5-/m1/s1

HIDE SMILES / InChI
Molecular Formula C6H8O6
Molecular Weight 176.1241
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Erythorbic acid, an epimer of L-ascorbic acid, is used in the United States as a food additive. It was studied, that erythorbic acid enhanced of iron absorption and could play a major role in enhancing iron bioavailability from mixed diets that include foods preserved with erythorbic acid. In addition, was investigated if the erythorbic acid could influence on the metabolism of vitamin C in young women, and obtained results showed, that prolonged ingestion of erythorbic acid had no effect on vitamin C uptake or clearance from the body.

Originator

Approval Year

2007
205
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Protective effect of ascorbic acid, isoascorbic acid and mannitol against tetracycline-induced nephrotoxicity.
1971 Jul
The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants.
2002 Mar
Patents

Patents

JP1070503A
3
JP2000023615A
3
JP2000106843A
3
JP2000116364A
3
JP2000236834A
5
JP2000253855A
3
JP2000290199A
28
JP2000354455A
3
JP2001008653A
3
JP2001031998A
3
JP2001131572A
3
JP2001206851A
3
JP2001288090A
3
JP2002097131A
3
JP2002125621A
3
JP2002218940A
4
JP2002262796A
3
JP2002326922A
7
JP2003171248A
3
JP2003171407A
3
JP2003183315A
3
JP2004000166A
3
JP2004024175A
3
JP2004230246A
3
JP2004315439A
3
JP2004516233A
21
JP2005029590A
5
JP2005097467A
3
JP2005097468A
3
JP2005117958A
3
JP2005126668A
3
JP2005137283A
3
JP2005139138A
3
JP2005146062A
3
JP2005146195A
3
JP2005168352A
7
JP2005204653A
3
JP2005225794A
3
JP2005531515A
7
JP2005535711A
5
JP2006067951A
5
JP2006076890A
3
JP2006089422A
4
JP2006257192A
3
JP2006282740A
3
JP2006290926A
3
JP2006345797A
3
JP2006346789A
3
JP2007031369A
7
JP2007260274A
3
JP2007508802A
4

Sample Use Guides

In Vivo Use Guide
Young women were fed diets that contained controlled amounts of erythorbic acid and ascorbic acid.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:21:33 GMT 2023
Edited
by admin
on Fri Dec 15 15:21:33 GMT 2023
Record UNII
311332OII1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ERYTHORBIC ACID
FCC   FHFI   HSDB   II   INCI   MART.   USP-RS  
INCI  
Official Name English
D-ERYTHRO-HEX-2-ENOIC ACID GAMMA-LACTONE
Common Name English
ISOASCORBIC-ACID
Common Name English
FEMA NO. 2410
Code English
(5R)-5-((1R)-1,2-DIHYDROXYETHYL)-3,4-DIHYDROXYFURAN-2(5H)-ONE
Systematic Name English
ERYTHORBIC ACID [FHFI]
Common Name English
INS-315
Code English
ERYTHORBIC ACID [USP-RS]
Common Name English
D-ISOASCORBIC ACID
Common Name English
ERYTHORBIC ACID [INCI]
Common Name English
ASCORBIC ACID IMPURITY F [EP IMPURITY]
Common Name English
D-ERYTHRO-HEX-2-ENONIC ACID, .GAMMA.-LACTONE
Common Name English
ERYTHORBIC ACID [FCC]
Common Name English
ISOASCORBIC ACID
MI  
Common Name English
NSC-8117
Code English
INS NO.315
Code English
ERYTHORBIC ACID [II]
Common Name English
2,3-DIDEHYDRO-D-ERYTHRO-HEXONO-1,4-LACTONE
Common Name English
ISOASCORBIC ACID [MI]
Common Name English
ERYTHORBIC ACID [HSDB]
Common Name English
ERYTHORBIC ACID [MART.]
Common Name English
ERYTHORBATE
Common Name English
D-ARABOASCORBIC ACID
Common Name English
SACCHAROSONIC ACID
Common Name English
E-315
Code English
Classification Tree Code System Code
CODEX ALIMENTARIUS (GSFA) INS-315
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
NCI_THESAURUS C275
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
EPA PESTICIDE CODE 600396
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
JECFA EVALUATION INS-315
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
Code System Code Type Description
ECHA (EC/EINECS)
201-928-0
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
SMS_ID
100000174936
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
PUBCHEM
54675810
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
MERCK INDEX
m6441
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY Merck Index
NSC
8117
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
WIKIPEDIA
Erythorbic acid
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
NCI_THESAURUS
C79902
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
EPA CompTox
DTXSID6026537
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
MESH
C005056
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
RXCUI
1356145
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY RxNorm
DAILYMED
311332OII1
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
RXCUI
1356146
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
ALTERNATIVE
FDA UNII
311332OII1
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
HSDB
584
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
CAS
89-65-6
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
RS_ITEM_NUM
1241823
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
CHEBI
51438
Created by admin on Fri Dec 15 15:21:33 GMT 2023 , Edited by admin on Fri Dec 15 15:21:33 GMT 2023
PRIMARY
Related Record Type Details
Structure of SODIUM ERYTHORBATE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of CALCIUM ASCORBATE
PARENT -> IMPURITY
Structure of ASCORBIC ACID
PARENT -> IMPURITY
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