PRISOTINOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H18N2O
Molecular Weight	194.2734
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NC(C)CC1=CC=C(O)C=N1

InChI

InChIKey=WQRPBKUCJBWQRT-UHFFFAOYSA-N

InChI=1S/C11H18N2O/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10/h4-5,7-9,13-14H,6H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C11H18N2O
Molecular Weight	194.2734
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1820879 | https://www.ncbi.nlm.nih.gov/pubmed/8410411

Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.

Originator

Approval Year

PubMed

Title	Date	PubMed
Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man.	1991	1820879

Patents

Sample Use Guides

In Vivo Use Guide

90, 200, or 600 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:49:06 GMT 2023` Edited by `admin` on `Fri Dec 15 15:49:06 GMT 2023`
Record UNII	ZPO6B92P5Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRISOTINOL

Official Name

English

prisotinol [INN]

Common Name

English

(±)-6-(2-(ISOPROPYLAMINO)PROPYL)-3-PYRIDINOL

Systematic Name

English

3-PYRIDINOL, 6-(2-((1-METHYLETHYL)AMINO)PROPYL)-

Systematic Name

English

2-(2-ISOPROPYLAMINOPROPYL)-5-PYRIDINOL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78322