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Details

Stereochemistry UNKNOWN
Molecular Formula C11H18N2O
Molecular Weight 194.2734
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRISOTINOL, (+)-

SMILES

CC(C)NC(C)CC1=CC=C(O)C=N1

InChI

InChIKey=WQRPBKUCJBWQRT-UHFFFAOYSA-N
InChI=1S/C11H18N2O/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10/h4-5,7-9,13-14H,6H2,1-3H3

HIDE SMILES / InChI
Molecular Formula C11H18N2O
Molecular Weight 194.2734
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.

Originator

Ciba-Geigy A.-G.
15
Sources: JP 55149260; 2-​Aminoalkyl-​5-​pyridinols; Nov 20, 1980

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man.
1991
Patents

Patents

20070122474
47
JP55149260
6

Sample Use Guides

In Vivo Use Guide
90, 200, or 600 mg
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:05:59 GMT 2025
Edited
by admin
on Mon Mar 31 23:05:59 GMT 2025
Record UNII
8Y6GD95UMZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PRISOTINOL, (+)-
Common Name English
3-PYRIDINOL, 6-(2-((1-METHYLETHYL)AMINO)PROPYL)-, (+)-
Preferred Name English
(+)-6-(2-((1-METHYLETHYL)AMINO)PROPYL)-3-PYRIDINOL
Common Name English
Code System Code Type Description
CAS
78152-32-6
Created by admin on Mon Mar 31 23:05:59 GMT 2025 , Edited by admin on Mon Mar 31 23:05:59 GMT 2025
PRIMARY
FDA UNII
8Y6GD95UMZ
Created by admin on Mon Mar 31 23:05:59 GMT 2025 , Edited by admin on Mon Mar 31 23:05:59 GMT 2025
PRIMARY
Related Record Type Details
Structure of PRISOTINOL
RACEMATE -> ENANTIOMER
Structure of PRISOTINOL, (-)-
ENANTIOMER -> ENANTIOMER
NIH
NCATS
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