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Details

Stereochemistry RACEMIC
Molecular Formula C11H18N2O.2ClH
Molecular Weight 267.195
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRISOTINOL DIHYDROCHLORIDE

SMILES

Cl.Cl.CC(C)NC(C)CC1=CC=C(O)C=N1

InChI

InChIKey=WWKMQPRSOJYBNS-UHFFFAOYSA-N
InChI=1S/C11H18N2O.2ClH/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10;;/h4-5,7-9,13-14H,6H2,1-3H3;2*1H

HIDE SMILES / InChI
Molecular Formula C11H18N2O
Molecular Weight 194.2734
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.

Originator

Ciba-Geigy A.-G.
15
Sources: JP 55149260; 2-​Aminoalkyl-​5-​pyridinols; Nov 20, 1980

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man.
1991
Patents

Patents

20070122474
47
JP55149260
6

Sample Use Guides

In Vivo Use Guide
90, 200, or 600 mg
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:11:38 GMT 2023
Edited
by admin
on Sat Dec 16 10:11:38 GMT 2023
Record UNII
PPP3N7B22F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PRISOTINOL DIHYDROCHLORIDE
Common Name English
3-PYRIDINOL, 6-(2-((1-METHYLETHYL)AMINO)PROPYL)-, HYDROCHLORIDE (1:2)
Systematic Name English
3-PYRIDINOL, 6-(2-((1-METHYLETHYL)AMINO)PROPYL)-, DIHYDROCHLORIDE
Common Name English
Code System Code Type Description
PUBCHEM
20138281
Created by admin on Sat Dec 16 10:11:38 GMT 2023 , Edited by admin on Sat Dec 16 10:11:38 GMT 2023
PRIMARY PUBCHEM
FDA UNII
PPP3N7B22F
Created by admin on Sat Dec 16 10:11:38 GMT 2023 , Edited by admin on Sat Dec 16 10:11:38 GMT 2023
PRIMARY
CAS
78152-28-0
Created by admin on Sat Dec 16 10:11:38 GMT 2023 , Edited by admin on Sat Dec 16 10:11:38 GMT 2023
SUPERSEDED
CAS
76906-72-4
Created by admin on Sat Dec 16 10:11:38 GMT 2023 , Edited by admin on Sat Dec 16 10:11:38 GMT 2023
PRIMARY
Related Record Type Details
Structure of PRISOTINOL
PARENT -> SALT/SOLVATE
Structure of PRISOTINOL DIHYDROCHLORIDE, (+)-
ENANTIOMER -> RACEMATE
Structure of PRISOTINOL DIHYDROCHLORIDE, (-)-
ENANTIOMER -> RACEMATE
NIH
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