PRISOTINOL DIHYDROCHLORIDE, (-)-

Details

Stereochemistry	UNKNOWN
Molecular Formula	C11H18N2O.2ClH
Molecular Weight	267.195
Optical Activity	( - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRISOTINOL DIHYDROCHLORIDE, (-)-

Structure Search

SMILES

Cl.Cl.CC(C)NC(C)CC1=CC=C(O)C=N1

InChI

InChIKey=WWKMQPRSOJYBNS-UHFFFAOYSA-N

InChI=1S/C11H18N2O.2ClH/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10;;/h4-5,7-9,13-14H,6H2,1-3H3;2*1H

HIDE SMILES / InChI

Molecular Formula	C11H18N2O
Molecular Weight	194.2734
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1820879 | https://www.ncbi.nlm.nih.gov/pubmed/8410411

Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.

Originator

Approval Year

PubMed

Title	Date	PubMed
Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man.	1991	1820879

Patents

Sample Use Guides

In Vivo Use Guide

90, 200, or 600 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:11:38 GMT 2023` Edited by `admin` on `Sat Dec 16 10:11:38 GMT 2023`
Record UNII	C3LFG625CK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRISOTINOL DIHYDROCHLORIDE, (-)-

Common Name

English

3-PYRIDINOL, 6-(2-((1-METHYLETHYL)AMINO)PROPYL)-, DIHYDROCHLORIDE, (-)-

Systematic Name

English

Code System Code Type Description

CAS

76906-73-5

Created by admin on Sat Dec 16 10:11:38 GMT 2023 , Edited by admin on Sat Dec 16 10:11:38 GMT 2023

PRIMARY

FDA UNII

C3LFG625CK

Created by admin on Sat Dec 16 10:11:38 GMT 2023 , Edited by admin on Sat Dec 16 10:11:38 GMT 2023

PRIMARY

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