U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry UNKNOWN
Molecular Formula C11H18N2O
Molecular Weight 194.2734
Optical Activity ( - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRISOTINOL, (-)-

SMILES

CC(C)NC(C)CC1=CC=C(O)C=N1

InChI

InChIKey=WQRPBKUCJBWQRT-UHFFFAOYSA-N
InChI=1S/C11H18N2O/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10/h4-5,7-9,13-14H,6H2,1-3H3

HIDE SMILES / InChI
Molecular Formula C11H18N2O
Molecular Weight 194.2734
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.

Originator

Ciba-Geigy A.-G.
15
Sources: JP 55149260; 2-​Aminoalkyl-​5-​pyridinols; Nov 20, 1980

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man.
1991
Patents

Patents

20070122474
47
JP55149260
6

Sample Use Guides

In Vivo Use Guide
90, 200, or 600 mg
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:26:46 GMT 2023
Edited
by admin
on Sat Dec 16 10:26:46 GMT 2023
Record UNII
Z7JEE5QDD2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PRISOTINOL, (-)-
Common Name English
3-PYRIDINOL, 6-(2-((1-METHYLETHYL)AMINO)PROPYL)-, (-)-
Systematic Name English
(-)-6-(2-((1-METHYLETHYL)AMINO)PROPYL)-3-PYRIDINOL
Common Name English
Code System Code Type Description
CAS
78152-30-4
Created by admin on Sat Dec 16 10:26:46 GMT 2023 , Edited by admin on Sat Dec 16 10:26:46 GMT 2023
PRIMARY
FDA UNII
Z7JEE5QDD2
Created by admin on Sat Dec 16 10:26:46 GMT 2023 , Edited by admin on Sat Dec 16 10:26:46 GMT 2023
PRIMARY
Related Record Type Details
Structure of PRISOTINOL
RACEMATE -> ENANTIOMER
Structure of PRISOTINOL, (+)-
ENANTIOMER -> ENANTIOMER
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966