Izalontamab Brengitecan

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:35:53 UTC 2023` Edited by `admin` on `Sat Dec 16 19:35:53 UTC 2023`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	UC2FX6YY3P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Izalontamab Brengitecan

Official Name

English

Immunoglobulin G1-scFv_L-kappa dimer, anti-[Homo sapiens EGFR (epidermal growth factor receptor, receptor tyrosine-protein kinase erbB-1, ERBB1, HER1, HER-1, ERBB)] and anti-[Homo sapiens ERBB3 (receptor tyrosine protein kinase erbB-3, HER3)], chimeric a

Common Name

English

izalontamab brengitecan [INN]

Common Name

English

Fused G1-scFv heavy-lambda heavy chain chimeric and Homo sapiens (1-702) [gamma1 heavy chain anti-EGFR chimeric (1-448) [VH (Mus musculus IGHV2-2*03 (93.8%) -(IGHD) -IGHJ3*01 (92.9%) A128>S (119), CDR-IMGT [8.7.13] (26-33.51-57.96-108)) (1-119) -Homo sap

Common Name

English

Code System Code Type Description

INN

12678

Created by admin on Sat Dec 16 19:35:53 UTC 2023 , Edited by admin on Sat Dec 16 19:35:53 UTC 2023

PRIMARY

CAS

2760528-47-8

Created by admin on Sat Dec 16 19:35:53 UTC 2023 , Edited by admin on Sat Dec 16 19:35:53 UTC 2023

PRIMARY

FDA UNII

UC2FX6YY3P

Created by admin on Sat Dec 16 19:35:53 UTC 2023 , Edited by admin on Sat Dec 16 19:35:53 UTC 2023

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_613	2_681
2_480	2_554
2_369	2_427
2_263	2_323
2_222	4_214
2_146	2_202
2_22	2_95
1_613	1_681
1_480	1_554
1_369	1_427
1_263	1_323
1_222	3_214
1_231	2_231
1_228	2_228
1_146	1_202
1_22	1_95