U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 18:08:01 GMT 2023
Edited
by admin
on Sat Dec 16 18:08:01 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
S8YH2C9NLA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IZALONTAMAB
INN  
Official Name English
Anti-EGFR/HER3 Bispecific Antibody SI-B001
Common Name English
HER3 x EGFR SI-B001
Common Name English
izalontamab [INN]
Common Name English
IMMUNOGLOBULIN G1 (DE-448-LYSINE), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR) (HUMAN-MOUSE MONOCLONAL C225 .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS)2 FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR HER3
Common Name English
SI-B001
Code English
Code System Code Type Description
CAS
2559704-24-2
Created by admin on Sat Dec 16 18:08:02 GMT 2023 , Edited by admin on Sat Dec 16 18:08:02 GMT 2023
PRIMARY
NCI_THESAURUS
C178396
Created by admin on Sat Dec 16 18:08:02 GMT 2023 , Edited by admin on Sat Dec 16 18:08:02 GMT 2023
PRIMARY
FDA UNII
S8YH2C9NLA
Created by admin on Sat Dec 16 18:08:02 GMT 2023 , Edited by admin on Sat Dec 16 18:08:02 GMT 2023
PRIMARY
INN
12022
Created by admin on Sat Dec 16 18:08:02 GMT 2023 , Edited by admin on Sat Dec 16 18:08:02 GMT 2023
PRIMARY
From To
4_134 4_194
4_23 4_88
3_134 3_194
3_23 3_88
1_231 2_231
1_228 2_228
2_222 4_214
1_222 3_214
1_613 1_681
2_613 2_681
1_480 1_554
2_480 2_554
1_369 1_427
2_369 2_427
1_263 1_323
2_263 2_323
1_146 1_202
2_146 2_202
1_22 1_95
2_22 2_95
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_88
N 1_299
N 2_88
N 2_299
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
CONJUGATE -> PARENT
Related Record Type Details
ACTIVE MOIETY
antineoplastic
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL