U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 23:01:28 UTC 2021
Edited
by admin
on Sat Jun 26 23:01:28 UTC 2021
Protein Type ENZYME
Protein Sub Type TYROSINE KINASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
RSO83C9PIA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3
Common Name English
PROTO-ONCOGENE-LIKE PROTEIN C-ERBB-3
Common Name English
HER3
Common Name English
ERBB3
Common Name English
TYROSINE KINASE-TYPE CELL SURFACE RECEPTOR HER3
Common Name English
Code System Code Type Description
PHAROS
P21860
Created by admin on Sat Jun 26 23:01:29 UTC 2021 , Edited by admin on Sat Jun 26 23:01:29 UTC 2021
PRIMARY
UNIPROT
P21860
Created by admin on Sat Jun 26 23:01:29 UTC 2021 , Edited by admin on Sat Jun 26 23:01:29 UTC 2021
PRIMARY
FDA UNII
RSO83C9PIA
Created by admin on Sat Jun 26 23:01:29 UTC 2021 , Edited by admin on Sat Jun 26 23:01:29 UTC 2021
PRIMARY
From To
1_10 1_37
1_137 1_164
1_167 1_175
1_171 1_183
1_191 1_199
1_195 1_207
1_208 1_216
1_212 1_224
1_227 1_236
1_240 1_267
1_271 1_282
1_286 1_301
1_304 1_308
1_481 1_490
1_485 1_498
1_501 1_510
1_514 1_530
1_533 1_546
1_537 1_554
1_557 1_566
1_570 1_591
1_594 1_602
1_598 1_610
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_107
N 1_231
N 1_334
N 1_389
N 1_395
N 1_418
N 1_450
N 1_503
N 1_547
N 1_597
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
ISU104 completely suppressed Heregulin HRG-induced phosphorylation
INHIBITOR -> TARGET
IgG1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) activity targeting HER2 and HER3 receptors.
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL