TELISOTUZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 23:02:58 GMT 2025` Edited by `admin` on `Mon Mar 31 23:02:58 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	R15ZW356HN
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

telisotuzumab [INN]

Preferred Name

English

TELISOTUZUMAB

Official Name

English

ABT-700

Code

English

TELISOTUZUMAB [USAN]

Common Name

English

Telisotuzumab [WHO-DD]

Common Name

English

HUMANIZED IGG1 ANTI-C-MET ANTIBODY

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HUMAN HEPATOCYTE GROWTH FACTOR RECEPTOR (HGF RECEPTOR, PROTO-ONCOGENE C-MET, SCATTER FACTOR RECEPTOR, TYROSINE-PROTEIN KINASE MET, EC=2.7.10.1))

Systematic Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN HEPATOCYTE GROWTH FACTOR RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL ABT-700 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL ABT-700 .KAPPA.-CHAIN, DIMER

Systematic Name

English

Code System Code Type Description

CAS

1781223-80-0

Created by admin on Mon Mar 31 23:02:58 GMT 2025 , Edited by admin on Mon Mar 31 23:02:58 GMT 2025

PRIMARY

INN

10366

Created by admin on Mon Mar 31 23:02:58 GMT 2025 , Edited by admin on Mon Mar 31 23:02:58 GMT 2025

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DRUG BANK

DB14838

Created by admin on Mon Mar 31 23:02:58 GMT 2025 , Edited by admin on Mon Mar 31 23:02:58 GMT 2025

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SMS_ID

100000174224

Created by admin on Mon Mar 31 23:02:58 GMT 2025 , Edited by admin on Mon Mar 31 23:02:58 GMT 2025

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USAN

EF-52

Created by admin on Mon Mar 31 23:02:58 GMT 2025 , Edited by admin on Mon Mar 31 23:02:58 GMT 2025

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FDA UNII

R15ZW356HN

Created by admin on Mon Mar 31 23:02:58 GMT 2025 , Edited by admin on Mon Mar 31 23:02:58 GMT 2025

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NCI_THESAURUS

C106262

Created by admin on Mon Mar 31 23:02:58 GMT 2025 , Edited by admin on Mon Mar 31 23:02:58 GMT 2025

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ChEMBL

CHEMBL3545419

Created by admin on Mon Mar 31 23:02:58 GMT 2025 , Edited by admin on Mon Mar 31 23:02:58 GMT 2025

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From	To
1_22	1_96
1_145	1_201
1_221	3_218
1_223	2_223
1_225	2_225
1_228	2_228
1_260	1_320
1_366	1_424
2_22	2_96
2_145	2_201
2_221	4_218
2_260	2_320
2_366	2_424
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					QA085PMU8Q

HEPATOCYTE GROWTH FACTOR RECEPTOR

TARGET -> INHIBITOR


					976X9VXC3Z

TELISOTUZUMAB VEDOTIN

CONJUGATE -> PARENT

Related Record Type Details


					R15ZW356HN

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO-ACID SUBSTITUTION	[1_1] [2_1]		GLUTAMINE	Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NON-GLYCOSYLATED(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL