Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 11:31:57 GMT 2023
by
admin
on
Sat Dec 16 11:31:57 GMT 2023
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Protein Sub Type | |
Sequence Type | COMPLETE |
Record UNII |
QA085PMU8Q
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Record Status |
Validated (UNII)
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Record Version |
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-
Download
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Common Name | English |
Code System | Code | Type | Description | ||
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P08581
Created by
admin on Sat Dec 16 11:31:59 GMT 2023 , Edited by admin on Sat Dec 16 11:31:59 GMT 2023
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PRIMARY | |||
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QA085PMU8Q
Created by
admin on Sat Dec 16 11:31:59 GMT 2023 , Edited by admin on Sat Dec 16 11:31:59 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
Ki
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
BINDING
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
COMPETITIVE INHIBITOR
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
BINDING
Kd
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET | |||
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ACTIVATOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
Little efficacy shown in Phase II trials.
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IN-VIVO
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INHIBITOR -> TARGET |
In vitro studies in human liver microsomes demonstrated that crizotinib is a time-dependent inhibitor of CYP3A.
INHIBITOR
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
Blocks HGF binding to receptor.
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
PRECLINICAL
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
IC50
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AGONIST -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET |
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INHIBITOR -> TARGET |
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Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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