U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 12:29:31 UTC 2023
Edited
by admin
on Sat Dec 16 12:29:31 UTC 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
OVI08ABI5H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT
Common Name English
PBT
Common Name English
SCFR
Common Name English
P145 C-KIT
Common Name English
PROTO-ONCOGENE C-KIT
Common Name English
TYROSINE-PROTEIN KINASE KIT
Common Name English
KIT
Common Name English
V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG
Common Name English
CD117
Common Name English
PIEBALD TRAIT PROTEIN
Common Name English
Code System Code Type Description
WIKIPEDIA
CD117
Created by admin on Sat Dec 16 12:29:32 UTC 2023 , Edited by admin on Sat Dec 16 12:29:32 UTC 2023
PRIMARY
UNIPROT
P10721
Created by admin on Sat Dec 16 12:29:32 UTC 2023 , Edited by admin on Sat Dec 16 12:29:32 UTC 2023
PRIMARY
EC (ENZYME CLASS)
EC 2.7.10.1
Created by admin on Sat Dec 16 12:29:32 UTC 2023 , Edited by admin on Sat Dec 16 12:29:32 UTC 2023
PRIMARY
FDA UNII
OVI08ABI5H
Created by admin on Sat Dec 16 12:29:32 UTC 2023 , Edited by admin on Sat Dec 16 12:29:32 UTC 2023
PRIMARY
From To
1_33 1_72
1_111 1_161
1_126 1_158
1_208 1_265
1_403 1_466
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_105
N 1_120
N 1_258
N 1_268
N 1_275
N 1_295
N 1_327
N 1_342
N 1_438
N 1_461
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INHIBITOR
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Structure of CEDIRANIB
INHIBITOR -> TARGET
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Briquilimab
INHIBITOR -> TARGET
Structure of FAMITINIB
INHIBITOR -> TARGET
INHIBITOR
Structure of NILOTINIB
INHIBITOR -> TARGET
INHIBITOR
Structure of DASATINIB
INHIBITOR -> TARGET
INHIBITOR
Structure of CRENOLANIB
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Kd
BINDING
Structure of IMATINIB
INHIBITOR -> TARGET
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Structure of SU-11652
INHIBITOR -> TARGET
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CDX-0158
INHIBITOR -> TARGET
Kd
Structure of IMATINIB
INHIBITOR -> TARGET
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INHIBITOR -> TARGET
INHIBITOR
Structure of FAMITINIB
INHIBITOR -> TARGET
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IC50
Structure of FLUORO-DASATINIB F-18
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INHIBITOR -> TARGET
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INHIBITOR -> TARGET
Kd (pKd=9.1); Target: KIT
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Structure of RIPRETINIB
INHIBITOR -> TARGET
Structure of DOVITINIB
INHIBITOR -> TARGET
IN-VITRO
IC50
Structure of ILORASERTIB
INHIBITOR -> TARGET
Structure of SERALUTINIB
INHIBITOR -> TARGET
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INHIBITOR -> TARGET
as a monohydrochloride salt
IN-VITRO
IC50
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
NIH
NCATS
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