RIPRETINIB

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H21BrFN5O2
Molecular Weight	510.358
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of RIPRETINIB

Structure Search

SMILES

CCN1C(=O)C(=CC2=C1C=C(NC)N=C2)C3=CC(NC(=O)NC4=CC=CC=C4)=C(F)C=C3Br

InChI

InChIKey=CEFJVGZHQAGLHS-UHFFFAOYSA-N

InChI=1S/C24H21BrFN5O2/c1-3-31-21-12-22(27-2)28-13-14(21)9-17(23(31)32)16-10-20(19(26)11-18(16)25)30-24(33)29-15-7-5-4-6-8-15/h4-13H,3H2,1-2H3,(H,27,28)(H2,29,30,33)

HIDE SMILES / InChI

Molecular Formula	C24H21BrFN5O2
Molecular Weight	510.358
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:07:32 GMT 2023` Edited by `admin` on `Sat Dec 16 11:07:32 GMT 2023`
Record UNII	9XW757O13D
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

RIPRETINIB

Official Name

English

RIPRETINIB [USAN]

Common Name

English

N-(4-BROMO-5-(1-ETHYL-7-(METHYLAMINO)-2-OXO-1,2-DIHYDRO-1,6-NAPHTHYRIDIN-3-YL)-2-FLUOROPHENYL)-N'-PHENYLUREA

Systematic Name

English

QINLOCK

Brand Name

English

UREA, N-(4-BROMO-5-(1-ETHYL-1,2-DIHYDRO-7-(METHYLAMINO)-2-OXO-1,6-NAPHTHYRIDIN-3-YL)-2-FLUOROPHENYL)-N'-PHENYL-

Systematic Name

English

ripretinib [INN]

Common Name

English

Ripretinib [WHO-DD]

Common Name

English

RIPRETINIB [ORANGE BOOK]

Common Name

English

DCC-2618

Code

English

RIPRETINIB [MI]

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/17/1936

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

FDA ORPHAN DRUG

447414

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

FDA ORPHAN DRUG

597617

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

Code System Code Type Description

INN

10808

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

LACTMED

Ripretinib

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

DAILYMED

9XW757O13D

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

NCI_THESAURUS

C124067

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

USAN

EF-104

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

EPA CompTox

DTXSID201027956

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

WIKIPEDIA

Ripretinib

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

RXCUI

2369389

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

MERCK INDEX

m12203

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

SMS_ID

100000177389

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

PUBCHEM

71584930

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

FDA UNII

9XW757O13D

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

CAS

1442472-39-0

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

DRUG BANK

DB14840

Created by admin on Sat Dec 16 11:07:32 GMT 2023 , Edited by admin on Sat Dec 16 11:07:32 GMT 2023

PRIMARY

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ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Tmax	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC				AT STEADY-STATE