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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 12:55:16 UTC 2023
Edited
by admin
on Sat Dec 16 12:55:16 UTC 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
O037NFL7YQ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HISTONE DEACETYLASE 1
Common Name English
HD1
Common Name English
HDAC1
Common Name English
RPD3L1
Common Name English
Code System Code Type Description
PHAROS
Q13547
Created by admin on Sat Dec 16 12:55:18 UTC 2023 , Edited by admin on Sat Dec 16 12:55:18 UTC 2023
PRIMARY
FDA UNII
O037NFL7YQ
Created by admin on Sat Dec 16 12:55:18 UTC 2023 , Edited by admin on Sat Dec 16 12:55:18 UTC 2023
PRIMARY
UNIPROT
Q13547
Created by admin on Sat Dec 16 12:55:18 UTC 2023 , Edited by admin on Sat Dec 16 12:55:18 UTC 2023
PRIMARY
Related Record Type Details
Structure of RICOLINOSTAT
WEAK INHIBITOR->TARGET
IC50
Structure of 5-(1-(4-(TERT-BUTYL)BENZYL)-1H-PYRAZOL-3-YL)-NHYDROXYPENTANAMIDE
INHIBITOR -> TARGET
Structure of PURINOSTAT
INHIBITOR -> TARGET
IN-VIVO
Structure of TUCIDINOSTAT
INHIBITOR -> TARGET
IC50
Structure of TACEDINALINE
INHIBITOR -> TARGET
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Structure of TINOSTAMUSTINE
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Structure of MOCETINOSTAT
INHIBITOR -> TARGET
Potent HDAC inhibitor with most potency for HDAC1 in a cell-free assay.
INHIBITOR
IC50
Structure of DACINOSTAT
INHIBITOR -> TARGET
Structure of APICIDIN
INHIBITOR -> TARGET
Structure of NANATINOSTAT
INHIBITOR -> TARGET
Structure of Zabadinostat
INHIBITOR -> TARGET
Structure of REC-2282
INHIBITOR -> TARGET
IC50
Structure of ENTINOSTAT
INHIBITOR -> TARGET
Enzymatic Inhibition
IC50
Structure of FR-135313
INHIBITOR -> TARGET
Structure of DOMATINOSTAT
INHIBITOR -> TARGET
4SC-202 is a selective class I HDAC inhibitor and also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
INHIBITOR
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Structure of BELINOSTAT
LIGAND->TARGET
Structure of BG-45
INHIBITOR -> TARGET
Structure of IVALTINOSTAT
INHIBITOR -> TARGET
Structure of N-HYDROXY-5-(1-(4-NITROBENZYL)-1H-PYRAZOL-3-YL)PENTANAMIDE
INHIBITOR -> TARGET
Structure of 5-(1-(4-BROMOBENZYL)-1H-PYRAZOL-3-YL)-NHYDROXYPENTANAMIDE
INHIBITOR -> TARGET
Structure of CITARINOSTAT
INHIBITOR -> TARGET
Structure of ROMIDEPSIN
INHIBITOR -> TARGET
Potent HDAC1 inhibitor in a cell-free assay.
INHIBITOR
IC50
Structure of PANOBINOSTAT
INHIBITOR -> TARGET
A PAN HDAC INHIBITOR.
IC50
Structure of PRACINOSTAT
INHIBITOR -> TARGET
Structure of QUISINOSTAT
INHIBITOR -> TARGET
Structure of FIMEPINOSTAT
INHIBITOR -> TARGET
CUDC-907 is a dual PI3K.ALPHA. and HDAC1 inhibitor. Phase 1.
INHIBITOR
IC50
Structure of OCID-4681
INHIBITOR -> TARGET
Structure of N-HYDROXY-3-(3-(PHENETHYLSULFAMOYL)PHENYL)ACRYLAMIDE
INHIBITOR -> TARGET
Structure of N-HYDROXY-5-(1-(4-(TRIFLUOROMETHYL)BENZYL)-1H-PYRAZOL-3-YL)PENTANAMIDE
INHIBITOR -> TARGET
Structure of VALPROIC ACID
INHIBITOR -> TARGET
Structure of VORINOSTAT
INHIBITOR -> TARGET
Structure of ABEXINOSTAT
INHIBITOR -> TARGET
Abexinostat (PCI-24781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 NM. Phase 1/2.
INHIBITOR
Ki
Structure of REMETINOSTAT
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
NIH
NCATS
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