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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H22N6O3
Molecular Weight 382.4164
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GDC-0326

SMILES

CC(C)N1N=CN=C1C2=CN3CCOC4=C(C=CC(O[C@@H](C)C(N)=O)=C4)C3=N2

InChI

InChIKey=SIKYDKLGPWRPMZ-LBPRGKRZSA-N
InChI=1S/C19H22N6O3/c1-11(2)25-19(21-10-22-25)15-9-24-6-7-27-16-8-13(28-12(3)17(20)26)4-5-14(16)18(24)23-15/h4-5,8-12H,6-7H2,1-3H3,(H2,20,26)/t12-/m0/s1

HIDE SMILES / InChI

Molecular Formula C19H22N6O3
Molecular Weight 382.4164
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: P42336
Gene ID: 5290.0
Gene Symbol: PIK3CA
Target Organism: Homo sapiens (Human)
0.2 nM [Ki]
Substance Class Chemical
Created
by admin
on Sat Dec 16 18:20:11 GMT 2023
Edited
by admin
on Sat Dec 16 18:20:11 GMT 2023
Record UNII
MPJ2JD8YZX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GDC-0326
Code English
PROPANAMIDE, 2-((5,6-DIHYDRO-2-(1-(1-METHYLETHYL)-1H-1,2,4-TRIAZOL-5-YL)IMIDAZO(1,2-D)(1,4)BENZOXAZEPIN-9-YL)OXY)-, (2S)-
Systematic Name English
Code System Code Type Description
CAS
1282514-88-8
Created by admin on Sat Dec 16 18:20:11 GMT 2023 , Edited by admin on Sat Dec 16 18:20:11 GMT 2023
PRIMARY
PUBCHEM
58204997
Created by admin on Sat Dec 16 18:20:11 GMT 2023 , Edited by admin on Sat Dec 16 18:20:11 GMT 2023
PRIMARY
FDA UNII
MPJ2JD8YZX
Created by admin on Sat Dec 16 18:20:11 GMT 2023 , Edited by admin on Sat Dec 16 18:20:11 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY