PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:37:37 GMT 2023` Edited by `admin` on `Sat Dec 16 11:37:37 GMT 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	40QZG29AA4
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM

Common Name

English

PI3-KINASE SUBUNIT DELTA

Common Name

English

PTDINS-3-KINASE SUBUNIT P110-DELTA

Common Name

English

PTDINS-3-KINASE SUBUNIT DELTA

Common Name

English

PIK3CD

Common Name

English

PI3K-DELTA

Common Name

English

PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE 110 KDA CATALYTIC SUBUNIT DELTA

Common Name

English

PIK3C.DELTA.

Common Name

English

Code System Code Type Description

UNIPROT

O00329

Created by admin on Sat Dec 16 11:37:40 GMT 2023 , Edited by admin on Sat Dec 16 11:37:40 GMT 2023

PRIMARY

PHAROS

O00329

Created by admin on Sat Dec 16 11:37:40 GMT 2023 , Edited by admin on Sat Dec 16 11:37:40 GMT 2023

PRIMARY

FDA UNII

40QZG29AA4

Created by admin on Sat Dec 16 11:37:40 GMT 2023 , Edited by admin on Sat Dec 16 11:37:40 GMT 2023

PRIMARY

Related Record Type Details


					YGE99UD9C2

WX-037

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					1MK0TQ597B

LAS-191954

INHIBITOR -> TARGET

Interaction Type:

COMPETITIVE INHIBITOR

Qualification:

IC50

Amount:


					38073MQB2A

UMBRALISIB

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					06H865SCMW

RV-1729

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					75658JDG29

PF-06843195

INHIBITOR -> TARGET

Qualification:

Amount:


					4W39NS61KI

PF-04691502

INHIBITOR -> TARGET


					05HYK3CV9N

LINPERLISIB

INHIBITOR -> TARGET

Amount:


					MPJ2JD8YZX

GDC-0326

INHIBITOR -> TARGET

Amount:


					S0GJ8VM4P9

PARSACLISIB HYDROCHLORIDE

INHIBITOR -> TARGET


					DW94IAT0LS

GSK-2636771

INHIBITOR -> TARGET

Amount:


					0ZM2Z182GD

BUPARLISIB

INHIBITOR -> TARGET


					08W5N2C97Q

ALPELISIB

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					F7WQK85U32

AUM-302

INHIBITOR -> TARGET

Comments:

HTRF technology assay

Qualification:

IC50

Amount:


					4M4E8NZ73C

GSK-2292767

INHIBITOR -> TARGET

Qualification:

Amount:


					987796874T

SONOLISIB

INHIBITOR -> TARGET


					CVL1685GPH

VOXTALISIB

INHIBITOR -> TARGET


					WI6V529FZ9

COPANLISIB

INHIBITOR -> TARGET

Interaction Type:

INHIBITOR

Qualification:

IC50

Amount:


					59784ZX4GD

BAY-1082439

INHIBITOR -> TARGET

Amount:


					YG57I8T5M0

IDELALISIB

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					19DG7G1U5Q

AMG-319

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					L22772Z9CP

LENIOLISIB

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					1C854K1MIJ

APITOLISIB

INHIBITOR -> TARGET


					64CW205BDD

SELETALISIB

INHIBITOR -> TARGET

Amount:


					RUJ6Z9Y0DT

DACTOLISIB

INHIBITOR -> TARGET


					C88817F47Y

SAMOTOLISIB

INHIBITOR -> TARGET

Amount:


					6K8FC2TF54

Roginolisib

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					1X8F5A3NA0

OMIPALISIB

INHIBITOR -> TARGET


					2K59L7G59M

DEZAPELISIB

INHIBITOR -> TARGET


					U09Q76B8VK

GS-9901

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					F3YMY7783P

Amdizalisib

INHIBITOR -> TARGET

Amount:


					K0068GK39A

ZSTK-474

INHIBITOR -> TARGET

Amount:


					OEP8JJ3OZR

NEMIRALISIB

INHIBITOR -> TARGET

Comments:

>1000-fold selectivity to other isoforms

Qualification:

IC50

Amount:


					610V23S0JI

DUVELISIB

INHIBITOR -> TARGET

Qualification:

Amount:


					OS7097575K

PARSACLISIB

INHIBITOR -> TARGET


					60ES45KTMK

PILARALISIB

INHIBITOR -> TARGET


					V929QJ7NQ8

RV-6153

INHIBITOR -> TARGET

Amount:


					2261HH611H

TENALISIB

INHIBITOR -> TARGET


					L08J2O299M

TASELISIB

INHIBITOR -> TARGET

Qualification:

Amount:


					ICY00EMP8P

PICTILISIB

INHIBITOR -> TARGET


					31M2U1DVID

LY-294002

INHIBITOR -> TARGET

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL