BEHENIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H44O2
Molecular Weight	340.5836
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCCCCCCC(O)=O

InChI

InChIKey=UKMSUNONTOPOIO-UHFFFAOYSA-N

InChI=1S/C22H44O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h2-21H2,1H3,(H,23,24)

HIDE SMILES / InChI

Molecular Formula	C22H44O2
Molecular Weight	340.5836
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/24257229 | https://www.truthinaging.com/ingredients/behenic-acid | https://www.ncbi.nlm.nih.gov/pubmed/24104695

Behenic acid is a saturated fatty acid that is derived from the oil extracts of plants and used as a component of conditioning agents. Behenic acid is also a part of a novel complex of lipophilic ingredients developed for the treatment of dry skin. The properties of behenic acid were studied in comparison to others fatty acids and it was found that behenic acid does not inhibit the UDP-glucuronosyltransferase (UGT) 1A1 enzyme. The high levels of behenic acid in patients with low-grade glial tumors is an important indicator of the persistence of tissue integrity and tissue resistance. Therefore, behenic acid levels can be a prognostic factor in glial tumors.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Glial tumors 2 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24257229	Diagnostic		Natural Metabolite	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
[Effect of various substrate nutrient on the spore germination and infective germ tube inducing of Pandora delphacis].	2001 Apr	12549032
Biosynthesis and structural characterization of medium-chain-length poly(3-hydroxyalkanoates) produced by Pseudomonas aeruginosa from fatty acids.	2001 Aug 20	11518582
Behenic acid is a cholesterol-raising saturated fatty acid in humans.	2001 Jan	11124748
[Determination of fatty acids in Malania oleifera oil by gas chromatography-mass spectrometry].	2001 Mar	12541659
Chemical and enzymatic transacylation of amide-linked FA of buttermilk gangliosides.	2003 Aug	14577665
Expression of the Arabidopsis ADS1 gene in Brassica juncea results in a decreased level of total saturated fatty acids.	2003 May	17156034
Calcification of intraocular implant lens surfaces.	2004 Feb 17	15803719
Observation of a two-step mechanism in the formation of a superstructure of cadmium-behenic acid Langmuir monolayer: evidence of an intermediate structure.	2004 Nov	15600579
Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate.	2005 Mar 11	15611129
[Research on chemical ingredients of the root from cultivar Aralia cordata Thunb].	2005 Nov	16514887
Evaluation of diagnostic markers for measles virus infection in the context of an outbreak in Spain.	2005 Oct	16207972
Potato phosphorylase catalyzed synthesis of amylose-lipid complexes.	2005 Sep-Oct	16153100
[Determination of fatty acids and organic acids in Ranunculus ternatus Thunb using GC-MS].	2006 Aug	17058970
pH-dependent kinetics of MgCl2 adsorption under a fatty-acid Langmuir film.	2006 Aug	16927026
The onset of brain injury and neurodegeneration triggers the synthesis of docosanoid neuroprotective signaling.	2006 Jul-Aug	16897369
The inhibitory action of long-chain fatty acids on the DNA binding activity of p53.	2006 Jun	16981429
Simultaneous determination of saponins and fatty acids in Ziziphus jujuba (Suanzaoren) by high performance liquid chromatography-evaporative light scattering detection and pressurized liquid extraction.	2006 Mar 10	16458908
Surface activity coefficients of spread monolayers of behenic acid salts at air-water interface.	2006 Nov 16	16904061
Characterization of the chemical composition of lotus plumule oil.	2006 Oct 4	17002438
Growth-inhibiting activity of active component isolated from Terminalia chebula fruits against intestinal bacteria.	2006 Sep	16995525
Relationship between serum concentrations of saturated fatty acids and unsaturated fatty acids and the homeostasis model insulin resistance index in Japanese patients with type 2 diabetes mellitus.	2007 Aug	17878672
NMR analysis of the conformational properties of the trapped on-pathway folding intermediate of the bacterial immunity protein Im7.	2007 Feb 23	17188712
Stearic acid-rich interesterified fat and trans-rich fat raise the LDL/HDL ratio and plasma glucose relative to palm olein in humans.	2007 Jan 15	17224066
Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes.	2007 Mar	17180682
Self-assembly in monoelaidin aqueous dispersions: direct vesicles to cubosomes transition.	2008	19015726
Simultaneous lipidomic analysis of three families of bioactive lipid mediators leukotrienes, resolvins, protectins and related hydroxy-fatty acids by liquid chromatography/electrospray ionisation tandem mass spectrometry.	2008	18059001
Calcium triggered L alpha-H2 phase transition monitored by combined rapid mixing and time-resolved synchrotron SAXS.	2008 Apr 30	18446202
The homeodomain derived peptide Penetratin induces curvature of fluid membrane domains.	2008 Apr 9	18398464
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.	2008 Jan 9	18046455
Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90.	2008 Jul 25	18492664
Nutritional quality evaluation of velvet bean seeds (Mucuna pruriens) exposed to gamma irradiation.	2008 Jun	17852489
The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression.	2008 Nov 16	19014610
[Study on chemical constituents of Smallanthus sonchifolius].	2008 Oct	19230402
On the low-temperature onset of molecular flexibility in lipid bilayers seen by Raman scattering.	2008 Oct 2	18774854
Nutritional and technological characteristics of olive (Olea europea L.) fruit and oil: two varieties growing in two different locations of Turkey.	2009 Aug	19337877
Very long chain fatty acid levels in patients diagnosed with multiple sclerosis.	2009 Dec	19965514
Analysis of sterols and fatty acids in natural and cultured Cordyceps by one-step derivatization followed with gas chromatography-mass spectrometry.	2009 Jul 12	19339130
AFM and multiple transmission-reflection infrared spectroscopy (MTR-IR) studies on formation of air-stable supported lipid bilayers.	2009 Mar	19399256
Root suberin forms an extracellular barrier that affects water relations and mineral nutrition in Arabidopsis.	2009 May	19461889
Fat malabsorption in cystic fibrosis: comparison of quantitative fat assay and a novel assay using fecal lauric/behenic acid.	2010 Apr	20179641
Serum fatty acids and cardiovascular risk factors in sudden sensorineural hearing loss: a case-control study.	2010 Feb	20336917
Chlamydomonas as a "new" organism for biodiesel production.	2010 Mar	19945866
Safety and adequacy of a semi-elemental formula for children with gastro-intestinal disease.	2010 Mar	19408097
Diffraction properties of periodic lattices under free electron laser radiation.	2010 Mar 26	20366545

Patents

Sample Use Guides

In Vivo Use Guide

Behenic acid is a part of conditioning agent

Route of Administration: Topical

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Wed Jul 05 22:41:29 UTC 2023` Edited by `admin` on `Wed Jul 05 22:41:29 UTC 2023`
Record UNII	H390488X0A
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BEHENIC ACID

Official Name

English

GLYCON B-70

Brand Name

English

HYDROFOL 2022-55

Brand Name

English

HYSTRENE 5522

Brand Name

English

N-DOCOSANOIC ACID

Common Name

English

PRIFRAC 2989

Brand Name

English

HYSTRENE 9022

Brand Name

English

PRIFRAC 2987

Brand Name

English

1-DOCOSANOIC ACID

Systematic Name

English

EDENOR C 22-85R

Brand Name

English

CRODACID B

Brand Name

English

DOCOSANOIC ACID [HSDB]

Common Name

English

NAA 222S

Code

English

BEHENIC ACID [INCI]

Common Name

English

C22:0

Common Name

English

BEHENIC ACID (CONSTITUENT OF BORAGE SEED OIL) [DSC]

Common Name

English

GLYCON B 70

Brand Name

English

BEHENIC ACID [MI]

Common Name

English

EXL 5

Code

English

B 95

Code

English

HYDROFOL ACID 560

Brand Name

English

BEHENATE

Common Name

English

ORISTAR BA

Brand Name

English

NAA 22S

Code

English

DOCOSANOIC ACID

Systematic Name

English

NSC-32364

Code

English

Classification Tree Code System Code

LOINC

30198-6