U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C27H44O3
Molecular Weight 416.6365
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of CALCITRIOL

SMILES

C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C

InChI

InChIKey=GMRQFYUYWCNGIN-NKMMMXOESA-N
InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1

HIDE SMILES / InChI

Molecular Formula C27H44O3
Molecular Weight 416.6365
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 6 / 6
E/Z Centers 2
Optical Activity UNSPECIFIED

Description
Curator's Comment: description was created based on several sources, including: https://www.drugs.com/cdi/calcitriol.html http://www.wikidoc.org/index.php/Calcitriol_(oral)

Calcitriol is vitamin D3. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body. Calcitriol is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people who have chronic kidney failure and are not receiving dialysis. Calcitriol is also used to treat calcium deficiency (hypocalcemia). The early signs and symptoms of vitamin D intoxication associated with hypercalcemia include: weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain and metallic taste. Cholestyramine has been reported to reduce intestinal absorption of fatsoluble vitamins; as such it may impair intestinal absorption of Calcitriol. Ketoconazole may inhibit both synthetic and catabolic enzymes of calcitriol.

CNS Activity

Curator's Comment: Circulating calcitriol can cross the blood brain barrier to a limited extent, and the brain itself may be able to synthesize calcitriol.

Originator

Curator's Comment: First obtained from chick intestine and designated as metabolite 4B

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
ROCALTROL

Approved Use

Predialysis Patients Calcitriol Capsules are indicated in the management of secondary hyperparathyroidism and resultant metabolic bone disease in patients with moderate to severe chronic renal failure (Ccr 15 to 55 mL/min) not yet on dialysis. In children, the creatinine clearance value must be corrected for a surface area of 1.73 square meters. A serum iPTH level of ≥100 pg/mL is strongly suggestive of secondary hyperparathyroidism. Dialysis Patients Calcitriol Capsules are indicated in the management of hypocalcemia and the resultant metabolic bone disease in patients undergoing chronic renal dialysis. In these patients, calcitriol administration enhances calcium absorption, reduces serum alkaline phosphatase levels, and may reduce elevated parathyroid hormone levels and the histological manifestations of osteitis fibrosa cystica and defective mineralization. Hypoparathyroidism Patients Calcitriol Capsules are also indicated in the management of hypocalcemia and its clinical manifestations in patients with postsurgical hypoparathyroidism, idiopathic hypoparathyroidism, and pseudohypoparathyroidism.

Launch Date

1978
Preventing
ROCALTROL

Approved Use

Predialysis Patients Calcitriol Capsules are indicated in the management of secondary hyperparathyroidism and resultant metabolic bone disease in patients with moderate to severe chronic renal failure (Ccr 15 to 55 mL/min) not yet on dialysis. In children, the creatinine clearance value must be corrected for a surface area of 1.73 square meters. A serum iPTH level of ≥100 pg/mL is strongly suggestive of secondary hyperparathyroidism. Dialysis Patients Calcitriol Capsules are indicated in the management of hypocalcemia and the resultant metabolic bone disease in patients undergoing chronic renal dialysis. In these patients, calcitriol administration enhances calcium absorption, reduces serum alkaline phosphatase levels, and may reduce elevated parathyroid hormone levels and the histological manifestations of osteitis fibrosa cystica and defective mineralization. Hypoparathyroidism Patients Calcitriol Capsules are also indicated in the management of hypocalcemia and its clinical manifestations in patients with postsurgical hypoparathyroidism, idiopathic hypoparathyroidism, and pseudohypoparathyroidism.

Launch Date

1978
Primary
VECTICAL

Approved Use

VECTICAL Ointment is indicated for the topical treatment of mild to moderate plaque psoriasis in adults 18 years and older.

Launch Date

1978
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
73.18 pg/mL
2 mg/cm² 2 times / day multiple, topical
dose: 2 mg/cm²
route of administration: topical
experiment type: multiple
co-administered:
CALCITRIOL plasma
Homo sapiens
population: unhealthy
age: Adolescents
sex: F+M
food status:
75.74 pg/mL
2 mg/cm² single, topical
dose: 2 mg/cm²
route of administration: topical
experiment type: single
co-administered:
CALCITRIOL plasma
Homo sapiens
population: unhealthy
age: Adolescents
sex: F+M
food status:
1100 pg/mL
38 μg 3 times / week multiple, oral
dose: 38 μg
route of administration: Oral
experiment type: MULTIPLE
co-administered: PACLITAXEL
CALCITRIOL plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
549.29 pg*h/mL
2 mg/cm² 2 times / day multiple, topical
dose: 2 mg/cm²
route of administration: topical
experiment type: multiple
co-administered:
CALCITRIOL plasma
Homo sapiens
population: unhealthy
age: Adolescents
sex: F+M
food status:
737.74 pg*h/mL
2 mg/cm² 2 times / day multiple, topical
dose: 2 mg/cm²
route of administration: topical
experiment type: multiple
co-administered:
CALCITRIOL plasma
Homo sapiens
population: unhealthy
age: Adolescents
sex: F+M
food status:
575.12 pg*h/mL
2 mg/cm² single, topical
dose: 2 mg/cm²
route of administration: topical
experiment type: single
co-administered:
CALCITRIOL plasma
Homo sapiens
population: unhealthy
age: Adolescents
sex: F+M
food status:
764.74 pg*h/mL
2 mg/cm² single, topical
dose: 2 mg/cm²
route of administration: topical
experiment type: single
co-administered:
CALCITRIOL plasma
Homo sapiens
population: unhealthy
age: Adolescents
sex: F+M
food status:
8100 pg × h/mL
38 μg 3 times / week multiple, oral
dose: 38 μg
route of administration: Oral
experiment type: MULTIPLE
co-administered: PACLITAXEL
CALCITRIOL plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
25 h
38 μg 3 times / week multiple, oral
dose: 38 μg
route of administration: Oral
experiment type: MULTIPLE
co-administered: PACLITAXEL
CALCITRIOL plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Androgen receptor signaling and vitamin D receptor action in prostate cancer cells.
2005-09-01
Vitamin D and phosphate regulate fibroblast growth factor-23 in K-562 cells.
2005-06
5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cells.
2005-05-15
Regulation of renal calcium receptor gene expression by 1,25-dihydroxyvitamin D3 in genetic hypercalciuric stone-forming rats.
2005-05
Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4.
2005-04-01
Modulation of CYP27B1 and CYP24 mRNA expression in bone is independent of circulating 1,25(OH)2D3 levels.
2005-04
Daily or intermittent calcitriol administration during growth hormone therapy in rats with renal failure and advanced secondary hyperparathyroidism.
2005-04
Mechanism and function of high vitamin D receptor levels in genetic hypercalciuric stone-forming rats.
2005-03
Pretreatment serum FGF-23 levels predict the efficacy of calcitriol therapy in dialysis patients.
2005-03
Amphiregulin is a novel growth factor involved in normal bone development and in the cellular response to parathyroid hormone stimulation.
2005-02-04
1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts.
2005-02
Human bladder as a novel target for vitamin D receptor ligands.
2005-02
Regulation of the human vitamin D3 receptor promoter in breast cancer cells is mediated through Sp1 sites.
2005-01-31
Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo.
2005-01-28
Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative.
2005-01
Type 2 iodothyronine selenodeiodinase is expressed throughout the mouse skeleton and in the MC3T3-E1 mouse osteoblastic cell line during differentiation.
2005-01
Targacept active conformation search: a new method for predicting the conformation of a ligand bound to its protein target.
2004-12-30
Calcitriol-induced prostate-derived factor: autocrine control of prostate cancer cell growth.
2004-12-20
The functional consequences of cross-talk between the vitamin D receptor and ERK signaling pathways are cell-specific.
2004-11-05
Calcium and calcitriol prophylaxis attenuates posttransplant bone loss.
2004-10-27
Role of uncoupling protein 2 (UCP2) expression and 1alpha, 25-dihydroxyvitamin D3 in modulating adipocyte apoptosis.
2004-09
Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts.
2004-08
Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency.
2004-08
Gene expression analysis suggests that 1,25-dihydroxyvitamin D3 reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosis.
2004-07-08
Differential regulation of osteogenic marker gene expression by Wnt-3a in embryonic mesenchymal multipotential progenitor cells.
2004-06
Improved anemia and reduced erythropoietin need by medical or surgical intervention of secondary hyperparathyroidism in hemodialysis patients.
2004-05
DNA microarray analysis of vitamin D-induced gene expression in a human colon carcinoma cell line.
2004-04-13
FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis.
2004-03
1,25(OH)2D3 inhibits bone marrow adipogenesis in senescence accelerated mice (SAM-P/6) by decreasing the expression of peroxisome proliferator-activated receptor gamma 2 (PPARgamma2).
2004-03
Leptin corrects increased gene expression of renal 25-hydroxyvitamin D3-1 alpha-hydroxylase and -24-hydroxylase in leptin-deficient, ob/ob mice.
2004-03
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism.
2004-02
Retinoblastoma protein and CCAAT/enhancer-binding protein beta are required for 1,25-dihydroxyvitamin D3-induced monocytic differentiation of HL60 cells.
2004-01-01
Structural determinants for vitamin D receptor response to endocrine and xenobiotic signals.
2004-01
Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm.
2003-11-21
Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity.
2003-09-12
9-cis retinoic acid accelerates calcitriol-induced osteocalcin production and promotes degradation of both vitamin D receptor and retinoid X receptor in human osteoblastic cells.
2003-08-15
Comparison of the gene expression profiles of monocytic versus granulocytic lineages of HL-60 leukemia cell differentiation by DNA microarray analysis.
2003-08-15
Effects of Seocalcitol (EB1089) on nitrosomethyl urea-induced rat mammary tumors.
2003-08
Gene expression of vitamin D hydroxylase and megalin in the remnant kidney of nephrectomized rats.
2003-08
Vitamin D enhances mitogenesis mediated by keratinocyte growth factor receptor in keratinocytes.
2003-06-01
1alpha,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-beta activity via phospholipase A2-dependent production of lysophospholipid.
2003-05
Inhibition of fatty acid synthase expression by 1alpha,25-dihydroxyvitamin D3 in prostate cancer cells.
2003-05
Regulation of 1-alpha, 25-dihydroxyvitamin D3 on interleukin-6 and interleukin-8 induced by sulfur mustard (HD) on human skin cells.
2003-05
Demonstration of UVB-induced synthesis of 1 alpha,25-dihydroxyvitamin D3 (calcitriol) in human skin by microdialysis.
2003-04
Paricalcitol versus calcitriol in the treatment of secondary hyperparathyroidism.
2003-04
EB1089: a new vitamin D analogue that inhibits the growth of breast cancer cells in vivo and in vitro.
1992-12-15
Potentiation of lipopolysaccharide-induced tumor necrosis factor-alpha expression by 1,25-dihydroxyvitamin D3.
1992-12-01
Dose-dependent effects of aluminum on osteocalcin synthesis in osteoblast-like ROS 17/2 cells in culture.
1992-12
A prospective trial of phosphate and 1,25-dihydroxyvitamin D3 therapy in symptomatic adults with X-linked hypophosphatemic rickets.
1992-09
Effect of 1,25-dihydroxyvitamin D3 on the female reproductive system in rats.
1992-08
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: The recommended initial dose of Calcitriol Injection, depending on the severity of the hypocalcemia and/or secondary hyperparathyroidism, is 1 mcg (0.02 mcg/kg) to 2 mcg administered intravenously three times weekly, approximately every other day. Doses as small as 0.5 mcg and as large as 4 mcg three times weekly have been used as an initial dose. Apply Calcitriol Ointment to affected areas twice daily, morning and evening. The maximum weekly dose should not exceed 200 grams. Calcitriol Ointment is not for oral, ophthalmic or intravaginal use.
Mice: Trans-calcitriol at 1.0, 2.0, and 4.0 mg/kg did not elicit any clinical effects after a single oral dose followed by 14 days of observation.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:09:10 GMT 2025
Edited
by admin
on Mon Mar 31 18:09:10 GMT 2025
Record UNII
FXC9231JVH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CALCITRIOL
EP   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
CALCIJEX
Preferred Name English
CALCITRIOL [MART.]
Common Name English
VECTICAL
Brand Name English
CALCITRIOL [VANDF]
Common Name English
ROCALTROL
Brand Name English
CALCITRIOL [USP MONOGRAPH]
Common Name English
CALCITRIOL [EP MONOGRAPH]
Common Name English
(1S,3R,5Z,7E)-9,10-SECOCHOLESTA-5,7,10-TRIENE-1,3,25-TRIOL
Common Name English
CALCITRIOL [USP-RS]
Common Name English
RO-21-5535
Code English
CALCITRIOL [JAN]
Common Name English
RO-215535
Code English
Calcitriol [WHO-DD]
Common Name English
CALCITRIOL [HSDB]
Common Name English
CALCITRIOL [ORANGE BOOK]
Common Name English
calcitriol [INN]
Common Name English
1,25-DIHYDROXY VITAMIN D3
Common Name English
1,25-HYDROXYLATED VITAMIN D
Common Name English
1,25-DIHYDROXYVITAMIN D3
Common Name English
RO 21-5535
Code English
CALCITRIOL [USAN]
Common Name English
CALCITRIOL [MI]
Common Name English
9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, (1.ALPHA.,3.BETA.,5Z,7E)-
Common Name English
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1?,3?,25-triol
Common Name English
1,25-DIHYDROXYCHOLECALCIFEROL, (1ALPHA)-
Common Name English
Classification Tree Code System Code
NDF-RT N0000006996
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
WHO-VATC QD05AX03
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
NCI_THESAURUS C39713
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
LOINC 1649-3
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
LIVERTOX 140
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
NDF-RT N0000006996
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
WHO-ATC A11CC04
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
NDF-RT N0000006996
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
NDF-RT N0000006996
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
LOINC 14566-4
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
NDF-RT N0000175908
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
WHO-VATC QA11CC04
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
WHO-ATC D05AX03
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
NCI_THESAURUS C1934
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
Code System Code Type Description
IUPHAR
2779
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
ECHA (EC/EINECS)
250-963-8
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
PUBCHEM
5280453
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
SMS_ID
100000092790
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
WIKIPEDIA
CALCITRIOL
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
CHEBI
17823
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
MERCK INDEX
m2917
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY Merck Index
DRUG BANK
DB00136
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
RS_ITEM_NUM
1086301
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
MESH
D002117
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
EPA CompTox
DTXSID5022722
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
INN
4393
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
ChEMBL
CHEMBL846
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
DAILYMED
FXC9231JVH
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
DRUG CENTRAL
466
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
NCI_THESAURUS
C330
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
HSDB
3482
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
EVMPD
SUB06047MIG
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
RXCUI
1894
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY RxNorm
FDA UNII
FXC9231JVH
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
LACTMED
Calcitriol
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
CAS
32222-06-3
Created by admin on Mon Mar 31 18:09:10 GMT 2025 , Edited by admin on Mon Mar 31 18:09:10 GMT 2025
PRIMARY
Related Record Type Details
METABOLIC ENZYME -> SUBSTRATE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
BASIS OF STRENGTH->SUBSTANCE
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
SALT/SOLVATE -> PARENT
SOLVATE->ANHYDROUS
TARGET -> ACTIVATOR
DERIVATIVE -> PARENT
BINDER->LIGAND
BINDING
Related Record Type Details
PARENT -> METABOLITE ACTIVE
PRODRUG -> METABOLITE ACTIVE
The conversion of calcidiol to calcitriol is catalyzed by the enzyme 25-hydroxyvitamin D3 1-alpha-hydroxylase (CYP27B1).
METABOLITE INACTIVE -> PARENT
MAJOR
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IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
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IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
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IMPURITY -> PARENT
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ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC