U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 16:46:48 UTC 2021
Edited
by admin
on Sat Jun 26 16:46:48 UTC 2021
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin CHIMERIC/HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
F3R7A4P04N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEPATUXIZUMAB MAFODOTIN
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY CONJUGATED TO AURISTATIN F
Systematic Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL ABT-806 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL ABT-806 LIGHT CHAIN, DIMER, TETRAKIS(THIOETHER) WITH N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDI
Systematic Name English
DEPATUXIZUMAB MAFODOTIN [WHO-DD]
Common Name English
DEPATUXIZUMAB MAFODOTIN [INN]
Common Name English
ABT-414
Code English
DEPATUXIZUMAB MAFODOTIN [USAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 433214
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
NCI_THESAURUS C129825
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
NCI_THESAURUS C2167
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
Code System Code Type Description
WIKIPEDIA
DEPATUXIZUMAB MAFODOTIN
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
PRIMARY
NCI_THESAURUS
C105612
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
PRIMARY
ChEMBL
CHEMBL3707277
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
PRIMARY
CAS
1585973-65-4
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
PRIMARY
FDA UNII
F3R7A4P04N
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
PRIMARY
DRUG BANK
DB11731
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
PRIMARY
INN
10263
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
PRIMARY
EVMPD
SUB181033
Created by admin on Sat Jun 26 16:46:48 UTC 2021 , Edited by admin on Sat Jun 26 16:46:48 UTC 2021
PRIMARY
From To
1_22 1_96
1_143 1_199
1_219 3_214
1_225 2_225
1_228 2_228
1_260 1_320
1_366 1_424
2_22 2_96
2_143 2_199
2_219 4_214
2_260 2_320
2_366 2_424
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details
CONJUGATE COMPONENT->CONJUGATE
TARGET->LIGAND
CONJUGATE COMPONENT->CONJUGATE
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:CALCULATED CHEMICAL
Molecular Formula CHEMICAL