U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 21:04:01 UTC 2021
Edited
by admin
on Sat Jun 26 21:04:01 UTC 2021
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin CHIMERIC/HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
W984C353CG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEPATUXIZUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL ABT-806 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL ABT-806 LIGHT CHAIN, DIMER
Common Name English
DEPATUXIZUMAB [WHO-DD]
Common Name English
ABT-806
Code English
ANTI-EGFR MAB ABT-806
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN HUMANIZED (1-446) (HUMANIZED VH (HOMO S
Systematic Name English
DEPATUXIZUMAB [INN]
Common Name English
ANTI-EGFR MOAB ABT-806
Common Name English
ANTI-EGFR MONOCLONAL ANTIBODY ABT-806
Common Name English
DEPATUXIZUMAB [USAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 361811
Created by admin on Sat Jun 26 21:04:01 UTC 2021 , Edited by admin on Sat Jun 26 21:04:01 UTC 2021
NCI_THESAURUS C20401
Created by admin on Sat Jun 26 21:04:01 UTC 2021 , Edited by admin on Sat Jun 26 21:04:01 UTC 2021
Code System Code Type Description
NCI_THESAURUS
C95206
Created by admin on Sat Jun 26 21:04:01 UTC 2021 , Edited by admin on Sat Jun 26 21:04:01 UTC 2021
PRIMARY
DRUG BANK
DB12826
Created by admin on Sat Jun 26 21:04:01 UTC 2021 , Edited by admin on Sat Jun 26 21:04:01 UTC 2021
PRIMARY
ChEMBL
CHEMBL3707294
Created by admin on Sat Jun 26 21:04:01 UTC 2021 , Edited by admin on Sat Jun 26 21:04:01 UTC 2021
PRIMARY
CAS
1471999-69-5
Created by admin on Sat Jun 26 21:04:01 UTC 2021 , Edited by admin on Sat Jun 26 21:04:01 UTC 2021
PRIMARY
FDA UNII
W984C353CG
Created by admin on Sat Jun 26 21:04:01 UTC 2021 , Edited by admin on Sat Jun 26 21:04:01 UTC 2021
PRIMARY
INN
10262
Created by admin on Sat Jun 26 21:04:01 UTC 2021 , Edited by admin on Sat Jun 26 21:04:01 UTC 2021
PRIMARY
From To
1_22 1_96
1_143 1_199
1_219 3_214
1_225 2_225
1_228 2_228
1_260 1_320
1_366 1_424
2_22 2_96
2_143 2_199
2_219 4_214
2_260 2_320
2_366 2_424
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details
CONJUGATE->CONJUGATE COMPONENT
TARGET -> INHIBITOR
CONJUGATE->CONJUGATE COMPONENT
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:CALCULATED CHEMICAL