U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 12:08:19 GMT 2023
Edited
by admin
on Sat Dec 16 12:08:19 GMT 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
EV0PWK6TT6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DELTA-TYPE OPIOID RECEPTOR
Common Name English
delta (DOP)
Common Name English
DOR-1
Common Name English
OPRD
Common Name English
Code System Code Type Description
PHAROS
P41143
Created by admin on Sat Dec 16 12:08:22 GMT 2023 , Edited by admin on Sat Dec 16 12:08:22 GMT 2023
PRIMARY
FDA UNII
EV0PWK6TT6
Created by admin on Sat Dec 16 12:08:22 GMT 2023 , Edited by admin on Sat Dec 16 12:08:22 GMT 2023
PRIMARY
UNIPROT
P41143
Created by admin on Sat Dec 16 12:08:22 GMT 2023 , Edited by admin on Sat Dec 16 12:08:22 GMT 2023
PRIMARY
From To
1_121 1_198
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_18
N 1_33
Related Record Type Details
AGONIST -> TARGET
INHIBITOR -> TARGET
IC50
PARTIAL AGONIST->TARGET
EMAX = 28% OF DAMGO
EC50
AGONIST -> TARGET
AGONIST -> TARGET
SELECTIVE
INHIBITOR -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
ANTAGONIST
RADIOLIGAND->TARGET
PARENT->INNOVATOR
AGONIST -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
AGONIST -> TARGET
RADIOLIGAND->OFF TARGET
Ki
AGONIST -> TARGET
SELECTIVE FOR DELTA AND DELTA-MU heteromers[
INHIBITOR -> TARGET
INHIBITOR -> TARGET
LIGAND->TARGET
WEAK BINDER
BINDING
IC50
PARTIAL AGONIST->TARGET
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Kd
INHIBITOR -> TARGET
NON-INHIBITOR->OFF TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
RADIOLIGAND->TARGET
Kd
RADIOLIGAND->TARGET
Kd
WEAK AGONIST->TARGET
INHIBITOR -> TARGET
AGONIST -> TARGET
Kd
AGONIST -> TARGET
In the MVD, C8813 could inhibit the electrically induced contraction, but weaker than in the GPI. Moreover, this inhibitory effect could antagonized by the δ-opioid receptor antagonist ICI174864. These results indicated C8813 also acted on δ-opioid receptor but less potent than on μ-opioid receptor.
INHIBITOR -> TARGET
AGONIST -> TARGET
Ki
INHIBITOR -> TARGET
BINDING
Ki
INHIBITOR -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
INHIBITOR->OFF-TARGET
Ki
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Assumed Kd similar to all opioid receptors
Kd
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL