Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Thu Jul 06 17:44:50 UTC 2023
by
admin
on
Thu Jul 06 17:44:50 UTC 2023
|
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
EV0PWK6TT6
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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P41143
Created by
admin on Thu Jul 06 17:44:52 UTC 2023 , Edited by admin on Thu Jul 06 17:44:52 UTC 2023
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PRIMARY | |||
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EV0PWK6TT6
Created by
admin on Thu Jul 06 17:44:52 UTC 2023 , Edited by admin on Thu Jul 06 17:44:52 UTC 2023
|
PRIMARY | |||
|
P41143
Created by
admin on Thu Jul 06 17:44:52 UTC 2023 , Edited by admin on Thu Jul 06 17:44:52 UTC 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_121 | 1_198 |
| Glycosylation Type | HUMAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_18 |
| N | 1_33 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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AGONIST -> TARGET |
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PARTIAL AGONIST->TARGET |
EMAX = 28% OF DAMGO
EC50
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AGONIST -> TARGET | |||
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AGONIST -> TARGET |
SELECTIVE
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INHIBITOR -> TARGET |
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AGONIST -> TARGET |
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AGONIST -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
ANTAGONIST
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RADIOLIGAND->TARGET | |||
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PARENT->INNOVATOR | |||
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AGONIST -> TARGET |
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AGONIST -> TARGET | |||
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INHIBITOR -> TARGET | |||
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AGONIST -> TARGET | |||
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AGONIST -> TARGET |
SELECTIVE FOR DELTA AND DELTA-MU heteromers[
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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PARTIAL AGONIST->TARGET | |||
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AGONIST -> TARGET | |||
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AGONIST -> TARGET | |||
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INHIBITOR -> TARGET | |||
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NON-INHIBITOR->OFF TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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RADIOLIGAND->TARGET |
Kd
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WEAK AGONIST->TARGET |
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INHIBITOR -> TARGET |
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AGONIST -> TARGET |
In the MVD, C8813 could inhibit the electrically induced contraction, but weaker than in the GPI. Moreover, this inhibitory effect could antagonized by the δ-opioid receptor antagonist ICI174864. These results indicated C8813 also acted on δ-opioid receptor but less potent than on μ-opioid receptor.
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INHIBITOR -> TARGET | |||
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AGONIST -> TARGET |
Ki
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INHIBITOR -> TARGET |
BINDING
Ki
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INHIBITOR -> TARGET |
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AGONIST -> TARGET | |||
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AGONIST -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
Assumed Kd similar to all opioid receptors
Kd
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
|