Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 12:08:19 GMT 2023
by
admin
on
Sat Dec 16 12:08:19 GMT 2023
|
Protein Sub Type | |
Sequence Origin | HUMAN |
Sequence Type | COMPLETE |
Record UNII |
EV0PWK6TT6
|
Record Status |
Validated (UNII)
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Record Version |
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-
Download
Name | Type | Language | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
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P41143
Created by
admin on Sat Dec 16 12:08:22 GMT 2023 , Edited by admin on Sat Dec 16 12:08:22 GMT 2023
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PRIMARY | |||
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EV0PWK6TT6
Created by
admin on Sat Dec 16 12:08:22 GMT 2023 , Edited by admin on Sat Dec 16 12:08:22 GMT 2023
|
PRIMARY | |||
|
P41143
Created by
admin on Sat Dec 16 12:08:22 GMT 2023 , Edited by admin on Sat Dec 16 12:08:22 GMT 2023
|
PRIMARY |
From | To |
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1_121 | 1_198 |
Glycosylation Type | HUMAN |
Glycosylation Link Type | Site |
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N | 1_18 |
N | 1_33 |
Related Record | Type | Details | ||
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AGONIST -> TARGET |
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INHIBITOR -> TARGET |
IC50
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PARTIAL AGONIST->TARGET |
EMAX = 28% OF DAMGO
EC50
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AGONIST -> TARGET | |||
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AGONIST -> TARGET |
SELECTIVE
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INHIBITOR -> TARGET |
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AGONIST -> TARGET |
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AGONIST -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
ANTAGONIST
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RADIOLIGAND->TARGET | |||
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PARENT->INNOVATOR | |||
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AGONIST -> TARGET |
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AGONIST -> TARGET | |||
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INHIBITOR -> TARGET | |||
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AGONIST -> TARGET | |||
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RADIOLIGAND->OFF TARGET |
Ki
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AGONIST -> TARGET |
SELECTIVE FOR DELTA AND DELTA-MU heteromers[
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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LIGAND->TARGET |
WEAK BINDER
BINDING
IC50
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PARTIAL AGONIST->TARGET | |||
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AGONIST -> TARGET | |||
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AGONIST -> TARGET | |||
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AGONIST -> TARGET |
Kd
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INHIBITOR -> TARGET | |||
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NON-INHIBITOR->OFF TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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RADIOLIGAND->TARGET |
Kd
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RADIOLIGAND->TARGET |
Kd
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WEAK AGONIST->TARGET |
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INHIBITOR -> TARGET |
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AGONIST -> TARGET |
Kd
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AGONIST -> TARGET |
In the MVD, C8813 could inhibit the electrically induced contraction, but weaker than in the GPI. Moreover, this inhibitory effect could antagonized by the δ-opioid receptor antagonist ICI174864. These results indicated C8813 also acted on δ-opioid receptor but less potent than on μ-opioid receptor.
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INHIBITOR -> TARGET | |||
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AGONIST -> TARGET |
Ki
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INHIBITOR -> TARGET |
BINDING
Ki
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INHIBITOR -> TARGET |
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AGONIST -> TARGET |
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AGONIST -> TARGET |
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INHIBITOR->OFF-TARGET |
Ki
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
Assumed Kd similar to all opioid receptors
Kd
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Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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MOL_WEIGHT | CHEMICAL |
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Molecular Formula | CHEMICAL |
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