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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 12:08:19 UTC 2023
Edited
by admin
on Sat Dec 16 12:08:19 UTC 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
EV0PWK6TT6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DELTA-TYPE OPIOID RECEPTOR
Common Name English
delta (DOP)
Common Name English
DOR-1
Common Name English
OPRD
Common Name English
Code System Code Type Description
PHAROS
P41143
Created by admin on Sat Dec 16 12:08:22 UTC 2023 , Edited by admin on Sat Dec 16 12:08:22 UTC 2023
PRIMARY
FDA UNII
EV0PWK6TT6
Created by admin on Sat Dec 16 12:08:22 UTC 2023 , Edited by admin on Sat Dec 16 12:08:22 UTC 2023
PRIMARY
UNIPROT
P41143
Created by admin on Sat Dec 16 12:08:22 UTC 2023 , Edited by admin on Sat Dec 16 12:08:22 UTC 2023
PRIMARY
From To
1_121 1_198
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_18
N 1_33
Related Record Type Details
Structure of PROGLUMIDE
AGONIST -> TARGET
Structure of NALOXONE
INHIBITOR -> TARGET
IC50
Structure of MP-135
PARTIAL AGONIST->TARGET
EMAX = 28% OF DAMGO
EC50
Structure of BW-942C
AGONIST -> TARGET
Structure of AZD-7268
AGONIST -> TARGET
SELECTIVE
Structure of NALTRINDOLE
INHIBITOR -> TARGET
Structure of TAN-67
AGONIST -> TARGET
Structure of CEBRANOPADOL
AGONIST -> TARGET
Structure of ELUXADOLINE
INHIBITOR -> TARGET
Structure of AT-076
INHIBITOR -> TARGET
ANTAGONIST
Structure of N-(C11)METHYLNALTRINDOLE
RADIOLIGAND->TARGET
Structure of CMX-020
PARENT->INNOVATOR
Structure of METENKEFALIN
AGONIST -> TARGET
Structure of BUTORPHANOL
AGONIST -> TARGET
Structure of NALDEMEDINE-CARBOXYLIC ACID
INHIBITOR -> TARGET
Structure of BUPRENORPHINE
AGONIST -> TARGET
Structure of LY-2795050 C-11
RADIOLIGAND->OFF TARGET
Ki
Structure of SNC-80
AGONIST -> TARGET
SELECTIVE FOR DELTA AND DELTA-MU heteromers[
Structure of NOR-NALDEMEDINE
INHIBITOR -> TARGET
Structure of NALDEMEDINE 3-O-.BETA.-D-GLUCURONIDE
INHIBITOR -> TARGET
Structure of U-50488
LIGAND->TARGET
WEAK BINDER
BINDING
IC50
Structure of SAMIDORPHAN
PARTIAL AGONIST->TARGET
Structure of AMDAKEFALIN
AGONIST -> TARGET
Structure of OXYCODONE
AGONIST -> TARGET
Structure of DADLE
AGONIST -> TARGET
Kd
Structure of NALDEMEDINE 6-O-.BETA.-D-GLUCURONIDE
INHIBITOR -> TARGET
Structure of FENTANYL
NON-INHIBITOR->OFF TARGET
Structure of NALBUPHINE
INHIBITOR -> TARGET
Structure of NALDEMEDINE
INHIBITOR -> TARGET
Structure of DADLE H-3
RADIOLIGAND->TARGET
Kd
Structure of Diprenorphine H-3
RADIOLIGAND->TARGET
Kd
Structure of DERMORPHIN
WEAK AGONIST->TARGET
Structure of MITRAGYNINE PSEUDOINDOXYL
INHIBITOR -> TARGET
Structure of DPDPE
AGONIST -> TARGET
Kd
Structure of THIOBROMADOL
AGONIST -> TARGET
In the MVD, C8813 could inhibit the electrically induced contraction, but weaker than in the GPI. Moreover, this inhibitory effect could antagonized by the δ-opioid receptor antagonist ICI174864. These results indicated C8813 also acted on δ-opioid receptor but less potent than on μ-opioid receptor.
Structure of NALMEFENE
INHIBITOR -> TARGET
Structure of MORPHINE
AGONIST -> TARGET
Ki
Structure of BUPRENORPHINE
INHIBITOR -> TARGET
BINDING
Ki
Structure of CYX-6
INHIBITOR -> TARGET
3-METHYLFENTANYL
AGONIST -> TARGET
Structure of ALVIMOPAN
AGONIST -> TARGET
Structure of LY-2795050
INHIBITOR->OFF-TARGET
Ki
Structure of CARBOXYFENTANYL
INHIBITOR -> TARGET
Structure of DIPRENORPHINE
INHIBITOR -> TARGET
Assumed Kd similar to all opioid receptors
Kd
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL
NIH
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