DELTA-TYPE OPIOID RECEPTOR

Approval Year

Substance Class	Protein
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	EV0PWK6TT6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DOR-1

Preferred Name

English

DELTA-TYPE OPIOID RECEPTOR

Common Name

English

delta (DOP)

Common Name

English

OPRD

Common Name

English

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Code System

Code

Type

Description

PHAROS

P41143

PRIMARY

FDA UNII

EV0PWK6TT6

PRIMARY

UNIPROT

P41143

PRIMARY

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Subunit 0

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From	To
1_121	1_198

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Glycosylation Type

HUMAN

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Glycosylation Link Type	Site
N	1_18
N	1_33

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Related Record

Type

Details


					EPL8W5565D

PROGLUMIDE

AGONIST -> TARGET

Amount:


					36B82AMQ7N

NALOXONE

INHIBITOR -> TARGET

Qualification:

IC50

Amount:

99 NANOMOLAR (average)


					A59U94JDE5

MP-135

PARTIAL AGONIST->TARGET

Comments:

EMAX = 28% OF DAMGO

Qualification:

EC50

Amount:

172 NANOMOLAR [170 to 174] (average)


					7ATC8US66S

BW-942C

AGONIST -> TARGET


					958Y70F3HQ

AZD-7268

AGONIST -> TARGET

Interaction Type:

SELECTIVE

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_352]				THREONINE PHOSPHATE	3L4WX7B1EI
AMINO ACID SUBSTITUTION	[1_147]				TYROSINE O-PHOSPHATE	2R86C98KDX

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL	ESTIMATED C1836H2907N479O498P2S26

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