U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C31H31FN8O2
Molecular Weight 566.6298
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PF-06263276

SMILES

CCc1cc(c(cc1-c2ccc3c(c2)[nH]nc3-c4[nH]c5CCN(Cc5n4)C(=O)c6cnc(cn6)N7CCCCC7)F)O

InChI

InChIKey=XDJGNPSZQSWJCV-UHFFFAOYSA-N
InChI=1S/C31H31FN8O2/c1-2-18-13-27(41)22(32)14-21(18)19-6-7-20-24(12-19)37-38-29(20)30-35-23-8-11-40(17-26(23)36-30)31(42)25-15-34-28(16-33-25)39-9-4-3-5-10-39/h6-7,12-16,41H,2-5,8-11,17H2,1H3,(H,35,36)(H,37,38)

HIDE SMILES / InChI

Molecular Formula C31H31FN8O2
Molecular Weight 566.6298
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Substance Class Chemical
Created
by admin
on Sat Jun 26 00:18:37 UTC 2021
Edited
by admin
on Sat Jun 26 00:18:37 UTC 2021
Record UNII
86YZ7HCC8V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PF-06263276
Common Name English
METHANONE, (2-(6-(2-ETHYL-5-FLUORO-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-3,4,6,7-TETRAHYDRO-5H-IMIDAZO(4,5-C)PYRIDIN-5-YL)(5-(1-PIPERIDINYL)-2-PYRAZINYL)-
Systematic Name English
(2-(6-(2-ETHYL-5-FLUORO-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-6,7-DIHYDRO-3H-IMIDAZO(4,5-C)PYRIDIN-5(4H)-YL)(5-(PIPERIDIN-1-YL)PYRAZIN-2-YL)METHANONE
Systematic Name English
Code System Code Type Description
PUBCHEM
135567296
Created by admin on Sat Jun 26 00:18:37 UTC 2021 , Edited by admin on Sat Jun 26 00:18:37 UTC 2021
PRIMARY
FDA UNII
86YZ7HCC8V
Created by admin on Sat Jun 26 00:18:37 UTC 2021 , Edited by admin on Sat Jun 26 00:18:37 UTC 2021
PRIMARY
CAS
1421502-62-6
Created by admin on Sat Jun 26 00:18:37 UTC 2021 , Edited by admin on Sat Jun 26 00:18:37 UTC 2021
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
IC50
TARGET -> INHIBITOR
IC50
TARGET -> INHIBITOR
IC50
TARGET -> INHIBITOR
IC50
Related Record Type Details
METABOLITE INACTIVE -> PARENT
Related Record Type Details
ACTIVE MOIETY