PF-06263276

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C31H31FN8O2
Molecular Weight	566.6286
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC1=CC(O)=C(F)C=C1C2=CC3=C(C=C2)C(=NN3)C4=NC5=C(CN(CC5)C(=O)C6=NC=C(N=C6)N7CCCCC7)N4

InChI

InChIKey=XDJGNPSZQSWJCV-UHFFFAOYSA-N

InChI=1S/C31H31FN8O2/c1-2-18-13-27(41)22(32)14-21(18)19-6-7-20-24(12-19)37-38-29(20)30-35-23-8-11-40(17-26(23)36-30)31(42)25-15-34-28(16-33-25)39-9-4-3-5-10-39/h6-7,12-16,41H,2-5,8-11,17H2,1H3,(H,35,36)(H,37,38)

HIDE SMILES / InChI

Molecular Formula	C31H31FN8O2
Molecular Weight	566.6286
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Janus Kinase (JAK) 2 Target ID: CHEMBL2363062 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27983835	Inhibitor 8504

Substance Class	Chemical Created by `admin` on `Wed Apr 02 05:12:08 GMT 2025` Edited by `admin` on `Wed Apr 02 05:12:08 GMT 2025`
Record UNII	86YZ7HCC8V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PF-06263276

Common Name

English

(2-(6-(2-ETHYL-5-FLUORO-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-6,7-DIHYDRO-3H-IMIDAZO(4,5-C)PYRIDIN-5(4H)-YL)(5-(PIPERIDIN-1-YL)PYRAZIN-2-YL)METHANONE

Preferred Name

English

METHANONE, (2-(6-(2-ETHYL-5-FLUORO-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-3,4,6,7-TETRAHYDRO-5H-IMIDAZO(4,5-C)PYRIDIN-5-YL)(5-(1-PIPERIDINYL)-2-PYRAZINYL)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

135567296

Created by admin on Wed Apr 02 05:12:08 GMT 2025 , Edited by admin on Wed Apr 02 05:12:08 GMT 2025

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FDA UNII

86YZ7HCC8V

Created by admin on Wed Apr 02 05:12:08 GMT 2025 , Edited by admin on Wed Apr 02 05:12:08 GMT 2025

PRIMARY

CAS