Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 14:27:46 GMT 2023
by
admin
on
Sat Dec 16 14:27:46 GMT 2023
|
Protein Type | ENZYME |
Protein Sub Type | DEACETYLASE |
Sequence Origin | HUMAN |
Sequence Type | COMPLETE |
Record UNII |
7YNS2RVD5Q
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
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O15379
Created by
admin on Sat Dec 16 14:27:48 GMT 2023 , Edited by admin on Sat Dec 16 14:27:48 GMT 2023
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PRIMARY | |||
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7YNS2RVD5Q
Created by
admin on Sat Dec 16 14:27:48 GMT 2023 , Edited by admin on Sat Dec 16 14:27:48 GMT 2023
|
PRIMARY |
Related Record | Type | Details | ||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
CUDC-907 is a dual PI3K.ALPHA. and HDAC3 inhibitor. Phase 1.
INDUCER
IC50
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INHIBITOR -> TARGET |
4SC-202 is a selective class I HDAC inhibitor and also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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WEAK INHIBITOR->TARGET |
Strongly inhibits HDAC3 in cell-free assays. Phase 3.
INHIBITOR
IC50
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WEAK INHIBITOR->TARGET |
IC50
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INHIBITOR -> TARGET |
Enzymatic Inhibition
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
IN-VIVO
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
Abexinostat (PCI-24781) is a modestly potent inhibitor to HDAC3. Phase 1/2.
INHIBITOR
MODERATE
|
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
Mocetinostat (MGCD0103) is a potent HDAC inhibitor with a
2- to 10- fold selectivity against HDAC3. Phase 2.
INHIBITOR
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INHIBITOR -> TARGET |
Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
---|---|---|---|---|---|---|
MOL_WEIGHT | CHEMICAL |
|