COAGULATION FACTOR IX HUMAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Approved Rx (2013)

First approved in 1990

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 18:34:50 GMT 2025` Edited by `admin` on `Mon Mar 31 18:34:50 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	6U90Y1795T
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

COAGULATION FACTOR IX HUMAN

Common Name

English

HUMAN COAGULATION FACTOR IX

Preferred Name

English

HUMAN COAGULATION FACTOR IX [EMA EPAR]

Common Name

English

Factor IX human [WHO-DD]

Common Name

English

HUMAN COAGULATION FACTOR IX [EP MONOGRAPH]

Common Name

English

MONONINE

Brand Name

English

ANTIHEMOPHILIC FACTOR B

Common Name

English

FACTOR IX HUMAN

Common Name

English

CHRISTMAS FACTOR

Common Name

English

NONAFACT

Brand Name

English

REPLENINE

Brand Name

English

COAGULATION FACTOR IX HUMAN (PLASMA DERIVED)

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

B02BD04

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

NDF-RT

N0000184169

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

EMA ASSESSMENT REPORTS

NONAFACT (AUTHORIZED: HEMOPHILIA B)

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

NCI_THESAURUS

C78311

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

FDA ORPHAN DRUG

36189

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C82269

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

DAILYMED

6U90Y1795T

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

SMS_ID

100000089087

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

FDA UNII

6U90Y1795T

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

CAS

181054-95-5

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

GENERIC (FAMILY)

NDF-RT

N0000175979

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

Increased Coagulation Activity [PE]

UNIPROT

P00740

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

DRUG BANK

DB13152

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

NDF-RT

N0000007914

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

Blood Coagulation Factors [Chemical/Ingredient]

EVMPD

SUB12030MIG

Created by admin on Mon Mar 31 18:34:50 GMT 2025 , Edited by admin on Mon Mar 31 18:34:50 GMT 2025

PRIMARY

From	To
1_18	1_23
1_51	1_62
1_56	1_71
1_73	1_82
1_88	1_99
1_95	1_109
1_111	1_124
1_132	1_289
1_206	1_222
1_336	1_350
1_361	1_389

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_157
N	1_167
O	1_38
O	1_53
O	1_159
O	1_169
O	1_179

Related Record Type Details


					Z5XCD5Q9RL

Etranacogene Dezaparvovec

GENE REPLACEMENT->TARGET

Amount:


					7NL2E3F6K3

ACTIVATOR -> TARGET

Amount:


					L7D6JMC51Y

LANACOGENE VOSIPARVOVEC

VECTOR->EXPRESSED PROTEIN

Amount:


					A57KX1VL5P

ALBUTREPENONACOG ALFA

ENZYME REPLACEMENT->TARGET

Amount:

COAGULATION FACTOR IX (HUMAN)

SUB_CONCEPT->SUBSTANCE

Amount:


					J177M7U2XK

ADLINACOGENE CIVAPARVOVEC

PARENT->INNOVATOR

Related Record Type Details


					6U90Y1795T

COAGULATION FACTOR IX HUMAN

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUION	[1_7] [1_8] [1_15] [1_17] [1_20] [1_21] [1_26] [1_27] [1_30] [1_33] [1_36] [1_40]		GLUTAMIC ACID		.GAMMA.-CARBOXYGLUTAMIC ACID	16FQV4RZKL
AMINO ACID SUBSTITUION	[1_158]		S		DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL