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Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 17:06:06 UTC 2021
Edited
by admin
on Sat Jun 26 17:06:06 UTC 2021
Protein Type RECEPTOR
Protein Sub Type HYDROXYTRYPTAMINE RECEPTOR
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
6E2Z4UWILI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
5-HYDROXYTRYPTAMINE RECEPTOR 2B
Common Name English
5-HT2B
Common Name English
Code System Code Type Description
UNIPROT
P41595
Created by admin on Sat Jun 26 17:06:08 UTC 2021 , Edited by admin on Sat Jun 26 17:06:08 UTC 2021
PRIMARY
FDA UNII
6E2Z4UWILI
Created by admin on Sat Jun 26 17:06:08 UTC 2021 , Edited by admin on Sat Jun 26 17:06:08 UTC 2021
PRIMARY
From To
1_128 1_207
1_350 1_353
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_30
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
AGONIST -> TARGET
Eletriptan binds with high affinity to 5-HT1B, 5-HT1D and 5-HT1F receptors, has modest affinity for 5-HT1A, 5-HT1E, 5-HT2B and 5-HT7 receptors
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Ki
INHIBITOR -> TARGET
AGONIST -> TARGET
Ki
INHIBITOR -> TARGET
INHIBITOR -> TARGET
AGONIST -> TARGET
We propose that preferential stimulation of valvular 5-HT2B receptors by norfenfluramine, ergot drugs, or 5-HT released from carcinoid tumors (with or without accompanying 5-HT2A receptor activation) may contribute to valvular fibroplasia in humans.
Ki
AGONIST -> TARGET
Ki
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL