SDZ SER-082

Details

Stereochemistry	UNKNOWN
Molecular Formula	C15H20N2
Molecular Weight	228.3327
Optical Activity	( + )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

[H][C@]12CCN(C)C[C@@]1([H])C3=CC=CC4=C3N(CC4)C2

InChI

InChIKey=YASBOGFWAMXINH-TZMCWYRMSA-N

InChI=1S/C15H20N2/c1-16-7-5-12-9-17-8-6-11-3-2-4-13(15(11)17)14(12)10-16/h2-4,12,14H,5-10H2,1H3/t12-,14-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C15H20N2
Molecular Weight	228.3327
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
5-hydroxytryptamine receptor 2B 12	Antagonist 2,778
5-hydroxytryptamine receptor 2C 26	Antagonist 2,778		7.8 null [pKd]

Substance Class	Chemical
Record UNII	M7FHF24Q22
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SDZ SER-082

Code

English

(+)-CIS 4,5,7A,8,9,10,11,11A-OCTAHYDRO-7H-10-METHYLINDOLO(1,7-BC)(2,6)-NAPHTHYRIDINE

Systematic Name

English

7H-INDOLO(1,7-BC)(2,6)NAPHTHYRIDINE, 4,5,7A,8,9,10,11,11A-OCTAHYDRO-10-METHYL-, CIS-(+)-

Systematic Name

English

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Code System

Code

Type

Description

PUBCHEM

9859407

PRIMARY

CAS

141474-59-1

PRIMARY

WIKIPEDIA

SDZ_SER-082

PRIMARY

IUPHAR

195

PRIMARY

FDA UNII

M7FHF24Q22

PRIMARY

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Related Record

Type

Details


					6E2Z4UWILI

5-HYDROXYTRYPTAMINE RECEPTOR 2B

TARGET -> INHIBITOR

Comments:

Acts as a mixed antagonist for the 5-HT2B and 5-HT2C serotonin receptors, with good selectivity over other serotonin receptor subtypes and slight preference for 5-HT2C over 5-HT2B.

Interaction Type:

ANTAGONIST


					W4BO00H6K6

5-HYDROXYTRYPTAMINE RECEPTOR 2C

TARGET -> INHIBITOR

Comments:

Acts as a mixed antagonist for the 5-HT2B and 5-HT2C serotonin receptors, with good selectivity over other serotonin receptor subtypes and slight preference for 5-HT2C over 5-HT2B.

Interaction Type:

ANTAGONIST

Showing 1 to 2 of 2 entries

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