NEAMINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C12H26N4O6
Molecular Weight	322.358
Optical Activity	( + )
Defined Stereocenters	10 / 10
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NEAMINE

SMILES

NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O

InChI

InChIKey=SYJXFKPQNSDJLI-HKEUSBCWSA-N

InChI=1S/C12H26N4O6/c13-2-5-8(18)9(19)6(16)12(21-5)22-11-4(15)1-3(14)7(17)10(11)20/h3-12,17-20H,1-2,13-16H2/t3-,4+,5-,6-,7+,8-,9-,10-,11-,12-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C12H26N4O6
Molecular Weight	322.358
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	10 / 10
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Show entries

Title	Date	PubMed
Screening for new compounds with antiherpes activity.	1984 Oct	6517562
Synthesis of biomimetic analogs of neomycin B: potential inhibitors of the HIV RNA Rev response element.	2000 Jan-Feb	10772716
Fluorinated aminoglycosides and their mechanistic implication for aminoglycoside 3'-phosphotransferases from Gram-negative bacteria.	2004 Mar 9	14992574
Chemoenzymatic synthesis and high-throughput screening of an aminoglycoside-polyamine library: identification of high-affinity displacers and DNA-binding ligands.	2004 Oct 6	15453764
Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities.	2005 Apr 15	15808482

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Patents

Substance Class	Chemical
Record UNII	5981U00LY0
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

ST 7

Preferred Name

English

NEAMINE

Common Name

English

NEBRAMYCIN X

Common Name

English

O-2,6-DIAMINO-2,6-DIDEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-1,3-DIAMINO-1,2,3-TRIDEOXY-D-MYO-INOSITOL

Common Name

English

D-STREPTAMINE, 2-DEOXY-4-O-(2,6-DIAMINO-2,6-DIDEOXY-.ALPHA.-D-GLUCOPYRANOSYL)-

Common Name

English

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Classification Tree

Code System

Code

Antibiotic

NCI_THESAURUS

C2363

Showing 1 to 1 of 1 entries

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Code System

Code

Type

Description

MERCK INDEX

m7784

PRIMARY

Merck Index

WIKIPEDIA

Neamine

PRIMARY

CHEBI

7489

PRIMARY

CAS

3947-65-7

PRIMARY

MESH

C488396

PRIMARY

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Amount:

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Showing 1 to 2 of 2 entries

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					5981U00LY0

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Showing 1 to 1 of 1 entries