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Details

Stereochemistry ACHIRAL
Molecular Formula C18H38O
Molecular Weight 270.4937
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of STEARYL ALCOHOL

SMILES

CCCCCCCCCCCCCCCCCCO

InChI

InChIKey=GLDOVTGHNKAZLK-UHFFFAOYSA-N
InChI=1S/C18H38O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h19H,2-18H2,1H3

HIDE SMILES / InChI

Molecular Formula C18H38O
Molecular Weight 270.4937
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Stearyl Alcohol is long chain fatty alcohol. Stearyl alcohol is prepared from stearic acid or some fats by the process of catalytic hydrogenation. It has low toxicity. Stearyl Alcohol is used in surface-active agents, lubricants, emulsions, resins, and USP ointments and as a substitute for cetyl alcohol and antifoaming agents. Stearyl Alcohol (synthetic) has been approved as a direct food additive (DFA) ingredient, to be used under the same manufacturing practices as the natrual alcohol product. It also has indirect food additive (IFA) status for use in food containers. Stearyl Alcohol is also used as an ingredient in over-the-counter (OTC) drugs of the miscellaneous external drug product category. It is considered to be safe at a concentration of 8 percent or less. Stearyl Alcohol is used in cosmetics as an emollient, stabilizer, antifoaming agent, emulsifier, and carrier. It is used as a water in oil (w/o) emulsifier to produce firm cosmetic products at ordinary temperatures.

CNS Activity

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
SAFETY BLANKET

Doses

AEs

PubMed

Sample Use Guides

In Vivo Use Guide
as a part of cream, losions
Route of Administration: Topical
In Vitro Use Guide
Stearyl alcohol induced expression of several secretory proteins including lipase, haemolysin-coregulated protein and nucleoside diphosphate kinase. Expression of these secreted proteins was upregulated at the transcriptional level. Stearyl alcohol also induced the synthesis of polyhydroxyalkanoate. Secretory protein EliA was required for all these responses of NT80 cells to stearyl alcohol.
Substance Class Chemical
Record UNII
2KR89I4H1Y
Record Status Validated (UNII)
Record Version