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Details

Stereochemistry RACEMIC
Molecular Formula C10H18O
Molecular Weight 154.2493
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of .ALPHA.-TERPINEOL

SMILES

CC1=CCC(CC1)C(C)(C)O

InChI

InChIKey=WUOACPNHFRMFPN-UHFFFAOYSA-N
InChI=1S/C10H18O/c1-8-4-6-9(7-5-8)10(2,3)11/h4,9,11H,5-7H2,1-3H3

HIDE SMILES / InChI
Molecular Formula C10H18O
Molecular Weight 154.2493
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description
Curator's Comment: description was created based on several sources, including: http://www.accessdata.fda.gov/scripts/FCN/fcnDetailNavigation.cfm?rpt=eafuslisting&id=2037 https://www.ncbi.nlm.nih.gov/pubmed/25893282 http://datasheets.scbt.com/sc-291877.pdf

Alpha-terpineol is a monoterpene found in the essential oils of several aromatic plant species. It has an anti-inflammatory and antioxidant effects. alpha-Terpineol is a fragrance ingredient used in decorative cosmetics, fine fragrances, shampoos, toilet soaps, and other toiletries as well as in non-cosmetic products such as household cleaners and detergents. alpha-Terpineol was approved by the FDA as a flavor.

Originator

Alder, K.|Vogt, W.
1
Sources: ftp://178.213.241.34/pub/Library/BOOKS/heap/SCI%20BOOKS/books/Chembooks/Mechanizms/Warren.pdf

Approval Year

2013
589
Targets

Targets

Primary TargetPharmacologyConditionPotency
Substrate
661
Activator
1447
Inhibitor
8504
 5.0 mM [IC50]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Transient cerebral ischemia
1
Sources: DOI: 10.22038/ijbms.2016.7596
 Preventing
Preclinical
Unknown

Approved Use

Unknown
Primary
Preclinical
Unknown

Approved Use

Unknown
Convulsions
72
Sources: DOI: 10.1080/13880200601028388
 Preventing
Preclinical
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Patents

Patents

WO2010046238A1
2

Sample Use Guides

In Vivo Use Guide
Sources: DOI: 10.22038/ijbms.2016.7596
α-Terpineol was given at doses of 50, 100, and 200 mg/kg, once daily for 7 days post ischemia.
Route of Administration: Intraperitoneal
In Vitro Use Guide
The rate of glucuronidation of 0.5 mM alpha-terpineol by human embryonic kidney 293 cells expressing UDP-glucuronosyltransferase 1.4 protein is 25 pmol/min/mg protein.
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:23:42 GMT 2025
Edited
by admin
on Mon Mar 31 18:23:42 GMT 2025
Record UNII
21334LVV8W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALPHA-TERPINEOL
FCC   HSDB  
Preferred Name English
.ALPHA.-TERPINEOL
FHFI   II   MI  
Common Name English
3-CYCLOHEXENE-1-METHANOL, ALPHA., .ALPHA., 4-TRIMETHYL-
Common Name English
ALFA-TERPINEOL
WHO-DD  
Common Name English
PC-593
Code English
FEMA NO. 3045
Code English
MIL-350
Code English
.ALPHA.-TERPINEOL [FHFI]
Common Name English
NSC-403665
Code English
ALPHA-TERPINEOL [HSDB]
Common Name English
ALPHA-TERPINEOL [FCC]
Common Name English
NSC-21449
Code English
.ALPHA.TERPINEOL
Common Name English
TERPIN MONOHYDRATE IMPURITY A [EP IMPURITY]
Common Name English
Alfa-terpineol [WHO-DD]
Common Name English
.ALPHA.-TERPINEOL [II]
Common Name English
.ALPHA.-TERPINEOL [MI]
Common Name English
PINE OIL-593
Common Name English
Classification Tree Code System Code
JECFA EVALUATION ALPHA-TERPINEOL
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
CFR 21 CFR 172.515
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
EC SCIENTIFIC COMMITTEE ON CONSUMER SAFETY OPINION SCCS/1459/11
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
EPA PESTICIDE CODE 224400
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
Code System Code Type Description
EVMPD
SUB12771MIG
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
CHEBI
22469
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
SMS_ID
100000085628
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
MERCK INDEX
m10583
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY Merck Index
NCI_THESAURUS
C77448
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
NSC
403665
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
PUBCHEM
17100
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
MESH
C016775
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
RXCUI
1371307
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY RxNorm
CAS
98-55-5
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
JECFA MONOGRAPH
352
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
FDA UNII
21334LVV8W
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
NSC
21449
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
EPA CompTox
DTXSID5026625
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
ECHA (EC/EINECS)
202-680-6
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
HSDB
5316
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
CONCEPT Industrial Aid
DAILYMED
21334LVV8W
Created by admin on Mon Mar 31 18:23:42 GMT 2025 , Edited by admin on Mon Mar 31 18:23:42 GMT 2025
PRIMARY
Related Record Type Details
MORINGA OLEIFERA LEAF OIL
PARENT -> ACTIVE CONSTITUENT ALWAYS PRESENT
>0.1% of chemical composition of the leaf essential oil from Moringa oleifera.
CLARY SAGE OIL
PARENT -> CONSTITUENT MAY BE PRESENT
ANISE OIL
PARENT -> CONSTITUENT MAY BE PRESENT
CANNABIS SATIVA SUBSP. INDICA TOP
PARENT -> CONSTITUENT ALWAYS PRESENT
Monoterpene Class
LAVENDER OIL
PARENT -> CONSTITUENT MAY BE PRESENT
PEUMUS BOLDUS LEAF
PARENT -> CONSTITUENT ALWAYS PRESENT
Structure of .ALPHA.-TERPINEOL, (+)-
ENANTIOMER -> RACEMATE
Structure of .ALPHA.-TERPINEOL, (-)-
ENANTIOMER -> RACEMATE
CORIANDER OIL
PARENT -> CONSTITUENT ALWAYS PRESENT
LEMON OIL, COLD PRESSED
PARENT -> CONSTITUENT MAY BE PRESENT
Related Record Type Details
Structure of TERPIN HYDRATE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
NIH
NCATS
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ACCESSIBILITY
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