Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 11:33:03 GMT 2023
by
admin
on
Sat Dec 16 11:33:03 GMT 2023
|
Protein Type | RECEPTOR |
Protein Sub Type | KINASE |
Sequence Origin | HUMAN |
Sequence Type | COMPLETE |
Record UNII |
1L68U00N7O
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
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1L68U00N7O
Created by
admin on Sat Dec 16 11:33:04 GMT 2023 , Edited by admin on Sat Dec 16 11:33:04 GMT 2023
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PRIMARY | |||
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P04629
Created by
admin on Sat Dec 16 11:33:04 GMT 2023 , Edited by admin on Sat Dec 16 11:33:04 GMT 2023
|
PRIMARY | |||
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P04629
Created by
admin on Sat Dec 16 11:33:04 GMT 2023 , Edited by admin on Sat Dec 16 11:33:04 GMT 2023
|
PRIMARY |
From | To |
---|---|
1_122 | 1_159 |
1_183 | 1_233 |
Glycosylation Type | HUMAN |
Glycosylation Link Type | Site |
---|---|
N | 1_35 |
N | 1_63 |
N | 1_89 |
N | 1_156 |
N | 1_170 |
N | 1_221 |
N | 1_230 |
N | 1_249 |
N | 1_286 |
N | 1_291 |
N | 1_306 |
N | 1_326 |
N | 1_369 |
Related Record | Type | Details | ||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
Active against NTRK gene fusions. Competitive to ATP binding site.
COMPETITIVE INHIBITOR
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IC50
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AGONIST -> TARGET |
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IC50
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RADIOLIGAND->TARGET |
Through a panel of 369 human kinases (no detectable kinase off-target at 1000-fold concentration over TrkB/C potency)
IC50
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INHIBITOR -> TARGET |
IC50
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AGONIST -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
IC50
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AGONIST -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
INHIBITOR
IC50
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INHIBITOR -> TARGET |
INHIBITOR
IC50
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INHIBITOR -> TARGET |
Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
---|---|---|---|---|---|---|
MOL_WEIGHT | CHEMICAL |
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