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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H19F2N5O
Molecular Weight 418.4292
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRACK F-18

SMILES

FC1=CC=CC(=C1)[C@H]2CCCN2C3=NN4C(C=C3)=NC=C4C(=O)NC5=CC=C([18F])C=C5

InChI

InChIKey=ZHJVVJVGTOZLTH-SCADIAGYSA-N
InChI=1S/C23H19F2N5O/c24-16-6-8-18(9-7-16)27-23(31)20-14-26-21-10-11-22(28-30(20)21)29-12-2-5-19(29)15-3-1-4-17(25)13-15/h1,3-4,6-11,13-14,19H,2,5,12H2,(H,27,31)/t19-/m1/s1/i24-1

HIDE SMILES / InChI

Molecular Formula C23H19F2N5O
Molecular Weight 418.4292
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 20:06:15 GMT 2023
Edited
by admin
on Sat Dec 16 20:06:15 GMT 2023
Record UNII
LZ8R7Q2ASK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRACK F-18
Common Name English
[18F]TRACK
Common Name English
Imidazo[1,2-b]pyridazine-3-carboxamide, N-[4-(fluoro-18F)phenyl]-6-[(2R)-2-(3-fluorophenyl)-1-pyrrolidinyl]-
Systematic Name English
N-[4-(Fluoro-18F)phenyl]-6-[(2R)-2-(3-fluorophenyl)-1-pyrrolidinyl]imidazo[1,2-b]pyridazine-3-carboxamide
Systematic Name English
Code System Code Type Description
CAS
2209122-25-6
Created by admin on Sat Dec 16 20:06:16 GMT 2023 , Edited by admin on Sat Dec 16 20:06:16 GMT 2023
PRIMARY
FDA UNII
LZ8R7Q2ASK
Created by admin on Sat Dec 16 20:06:16 GMT 2023 , Edited by admin on Sat Dec 16 20:06:16 GMT 2023
PRIMARY
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Through a panel of 369 human kinases (no detectable kinase off-target at 1000-fold concentration over TrkB/C potency)
IC50
TARGET->RADIOLIGAND
Through a panel of 369 human kinases (no detectable kinase off-target at 1000-fold concentration over TrkB/C potency)
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