AMIVANTAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	0JSR7Z0NB6
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

AMIVANTAMAB

Official Name

English

IMMUNOGLOBULIN G1 (413-LYSINE), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR) (HUMAN MONOCLONAL JNJ-61186372 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL JNJ-61186372 .KAPPA.-CHAIN, (234->228'),(237->231')-BIS(DISULFIDE) WITH IMMUNOGLOBULIN G1 (411-A

Common Name

English

Amivantamab [WHO-DD]

Common Name

English

CNTO-4424

Code

English

AMIVANTAMAB [JAN]

Common Name

English

Showing 1 to 5 of 9 entries

Previous1 2Next

Show entries

Classification Tree

Code System

Code

Biological Agent

NCI_THESAURUS

C1454

Showing 1 to 1 of 1 entries

Show entries

Code System

Code

Type

Description

FDA UNII

0JSR7Z0NB6

PRIMARY

NCI_THESAURUS

C124993

PRIMARY

WIKIPEDIA

Amivantamab

PRIMARY

RXCUI

2549199

PRIMARY

DAILYMED

0JSR7Z0NB6

PRIMARY

Showing 1 to 5 of 7 entries

Previous1 2Next

Show entries

From	To
1_22	1_96
1_152	1_208
1_228	3_214
1_234	2_228
1_237	2_231

Showing 1 to 5 of 16 entries

Previous1 2 3 4Next

Glycosylation Type

MAMMALIAN

Show entries

Showing 1 to 2 of 2 entries

Show entries

Related Record

Type

Details


					QA085PMU8Q

HEPATOCYTE GROWTH FACTOR RECEPTOR

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

Kd

Amount:

0.4 NANOMOLAR (average)


					RO03J093CP

EPIDERMAL GROWTH FACTOR RECEPTOR

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

Kd

Amount:

1.4 NANOMOLAR (average)


					3FJ2AHL47Q

EPIDERMAL GROWTH FACTOR RECEPTOR EXON 20 INSERTIONS

INHIBITOR -> TARGET

Comments:

Approved for treatment of EGFR EXON 20 insertions mutations in NSLC

Amount:

AMIVANTAMAB-VMJW

SUB_CONCEPT->SUBSTANCE

Amount:

Showing 1 to 4 of 4 entries

Show entries

Related Record

Type

Details


					0JSR7Z0NB6

ACTIVE MOIETY

Showing 1 to 1 of 1 entries

Show entries

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL	ESTIMATED C6472H10045O2019N1730S46
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 146000 Da (average)

Showing 1 to 2 of 2 entries