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Details

Stereochemistry ACHIRAL
Molecular Formula Ag.F.2H3N
Molecular Weight 160.9276
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SILVER DIAMMINE FLUORIDE

SMILES

[Ag+].[F-].N.N

InChI

InChIKey=FJKGRAZQBBWYLG-UHFFFAOYSA-M
InChI=1S/Ag.FH.2H3N/h;1H;2*1H3/q+1;;;/p-1

HIDE SMILES / InChI

Description
Curator's Comment:: description was created based on several sources, including http://www.thefreedictionary.com/silver+bromide | https://www.ncbi.nlm.nih.gov/pubmed/16833141 | https://www.hindawi.com/journals/jnp/2014/568635/

Silver iodide is an inorganic compound with the formula AgI. It is used as a photosensitive agent in photography, as a local antiseptic, as a chemical intermediate, and in cloud seeding for rain-making. The major hazards encountered in the use and handling of silver iodide stem from its toxicologic properties. Effects from exposure may include skin rashes, conjunctivitis, argyria (a permanent ashen-gray discoloration of skin, conjunctiva, and internal organs), headache, fever, hypersensitivity, laryngitis, and bronchitis.

Originator

Sources: Vestsi Akademii Navuk BSSR, Seryya Khimichnykh Navuk, Issue 2, Pages 69-73, Journal, 1990https://www.ncbi.nlm.nih.gov/pubmed/20429870
Curator's Comment:: The medical uses of silver date back to at least the time of Hippocrates

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Advantage Arrest Silver Diamine Fluoride

Approved Use

Unknown
Primary
Advantage Arrest Silver Diamine Fluoride

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
Curative
Unknown

Approved Use

Unknown
Curative
Unknown

Approved Use

Unknown
Primary
Colloidal silver iodide

Approved Use

Solution containing 5 to 49% of colloidal silver iodide have been employed in the treatment of infections of the mucous membranes. Ointments, usually containing 5%, have been used in inflammatory conditions of the eye, ear, and nose.
Primary
Colloidal silver iodide

Approved Use

Solution containing 5 to 49% of colloidal silver iodide have been employed in the treatment of infections of the mucous membranes. Ointments, usually containing 5%, have been used in inflammatory conditions of the eye, ear, and nose.
Palliative
Unknown

Approved Use

Antiseptic Wound Cauterization
Primary
Unknown

Approved Use

Prophylaxis of gonococcal ophthalmia neonatorum. AAP recommends use of topical silver nitrate, povidone-iodine, or possibly erythromycin for prophylaxis of nongonococcal nonchlamydial conjunctivitis in neonates, ideally administered shortly after birth.
PubMed

PubMed

TitleDatePubMed
A chemically intelligent antimicrobial coating for urologic devices.
2000 Feb
New disinfection and sterilization methods.
2001 Mar-Apr
Cleaning and decontamination efficacy of wiping cloths and silver dihydrogen citrate on food contact surfaces.
2012 Jul
UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent.
2016 Jan
An alternate technique of care using silver fluoride followed by stannous fluoride in the management of root caries in aged care.
2016 Mar-Apr
Directional growth of Ag nanorod from polymeric silver cyanide: A potential substrate for concentration dependent SERS signal enhancement leading to melamine detection.
2017 Aug 5
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment:: Toxicity data
Topical as a 1:80 dilution (30 ppm ionic silver).
Route of Administration: Topical
10 mkl volume of undiluted human norovirus 20% faecal suspension was mixed with 90 mkl of SDC (Silver Dihydrogen Citrate) for various contact times (15, 30, 60, 120, 300, 600 and 1800 s). At each sampling time point, 20 mkl of this solution was added to 180 mkl of 10% solution of Dey/Engley (D/E) neutralizing broth (Thermo Fisher Scientific, Waltham, MA). Samples were aliquoted and frozen at -80°C prior to nucleic acid extraction.
Name Type Language
SILVER DIAMMINE FLUORIDE
JAN  
Common Name English
SILVER DIAMINE FLUORIDE
Common Name English
SILVER DIAMMINE FLUORIDE [JAN]
Common Name English
DIAMMINE SILVER FLUORIDE
WHO-DD  
Common Name English
DIAMMINE SILVER FLUORIDE [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C28394
Created by admin on Sat Jun 26 13:30:21 UTC 2021 , Edited by admin on Sat Jun 26 13:30:21 UTC 2021
Code System Code Type Description
NCI_THESAURUS
C90990
Created by admin on Sat Jun 26 13:30:21 UTC 2021 , Edited by admin on Sat Jun 26 13:30:21 UTC 2021
PRIMARY
PUBCHEM
161820
Created by admin on Sat Jun 26 13:30:21 UTC 2021 , Edited by admin on Sat Jun 26 13:30:21 UTC 2021
PRIMARY
EVMPD
SUB13555MIG
Created by admin on Sat Jun 26 13:30:21 UTC 2021 , Edited by admin on Sat Jun 26 13:30:21 UTC 2021
PRIMARY
MESH
C024633
Created by admin on Sat Jun 26 13:30:21 UTC 2021 , Edited by admin on Sat Jun 26 13:30:21 UTC 2021
PRIMARY
FDA UNII
DDU19UEV1Y
Created by admin on Sat Jun 26 13:30:21 UTC 2021 , Edited by admin on Sat Jun 26 13:30:21 UTC 2021
PRIMARY
CAS
34445-07-3
Created by admin on Sat Jun 26 13:30:21 UTC 2021 , Edited by admin on Sat Jun 26 13:30:21 UTC 2021
PRIMARY