Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H8 |
Molecular Weight | 128.1705 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C1=CC2=C(C=C1)C=CC=C2
InChI
InChIKey=UFWIBTONFRDIAS-UHFFFAOYSA-N
InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H
DescriptionCurator's Comment: description was created based on several sources, including:
DOI: 10.1007/978-0-387-30160-0_7643
http://npic.orst.edu/factsheets/naphgen.html
http://www.cdc.gov/niosh/npg/npgd0439.html
Curator's Comment: description was created based on several sources, including:
DOI: 10.1007/978-0-387-30160-0_7643
http://npic.orst.edu/factsheets/naphgen.html
http://www.cdc.gov/niosh/npg/npgd0439.html
Naphthalene is a crystalline aromatic hydrocarbon usually obtained by distillation of coal tar. Once used as a moth repellent, it is now important as a reactant in the production of phthalic anhydride, which in turn is used for making plasticizers, alkyd resins, and polyester resins. Other fumigant uses of naphthalene include use in soil as a fumigant pesticide, and in attic spaces to repel animals. In the past, naphthalene was administered orally to kill parasitic worms in livestock. In humans, exposure to large amounts of naphthalene may damage or destroy red blood cells. Humans, particularly children, have developed this condition after ingesting mothballs or deodorant blocks containing naphthalene. Some of the symptoms of naphthalene poisoning are fatigue, lack of appetite, restlessness, and pale skin. Exposure to large amounts of naphthalene may also cause nausea, vomiting, diarrhea, blood in the urine, and jaundice (yellow coloration of the skin).
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: map00980 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8240407 |
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Target ID: GO:0030330 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10802220 |
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Target ID: GO:0034440 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10802220 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | EQUIOPATHICS WRM CLEAR Approved UseIndicated for the treatment of worm infestations |
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Palliative | ALLERGIES Approved UseUses for relief of allergy symptoms affecting the mucous membranes and skin |
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Palliative | NAPHTHALINUM Approved UseNaphtalinum helps in coryza and hay fever. |
PubMed
Title | Date | PubMed |
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Hydrocarbon deposition and soil microflora as affected by highway traffic. | 2001 |
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Synthesis and pharmacology of site specific cocaine abuse treatment agents: a new synthetic methodology for methylphenidate analogs based on the Blaise reaction. | 2001 Apr |
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A comparative study on the inhibition of human and bacterial kynureninase by novel bicyclic kynurenine analogues. | 2001 Apr |
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Occurrence and potential adverse effects of semivolatile organic compounds in streambed sediment, United States, 1992-1995. | 2001 Apr |
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Development of new urea-functionalized silica stationary phases. Characterization and chromatographic performance. | 2001 Apr 13 |
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Complete prediction of the 1H NMR spectrum of organic molecules by DFT calculations of chemical shifts and spin-spin coupling constants. | 2001 Apr 17 |
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Solid-state structures of group 1 and group 2 metal 1,5-naphthalenedisulfonates: systematic investigation of lamellar three-dimensional networks constructed by metal arenedisulfonate. | 2001 Aug |
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Efficient polycyclic aromatic hydrocarbons dihydroxylation in direct micellar systems. | 2001 Aug 5 |
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DDT, PAH and PCB in sediments from the intertidal zone of the Bohai Sea and the Yellow Sea. | 2001 Feb |
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Uptake of polycyclic aromatic hydrocarbon compounds by the gills of the bivalve mollusk Elliptio complanata. | 2001 Feb |
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Steric and electronic ligand perturbations in catalysis: asymmetric allylic substitution reactions using C2-symmetrical phosphorus-chiral (bi)ferrocenyl donors. | 2001 Feb 9 |
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[The toxicity variation of organic extracts in drinking water treatment processes]. | 2001 Jan |
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Oxidative coupling of O-silyl and O-alkyl enethers: application of the novel annulation sequence to the synthesis of fluorinated naphthaldehydes and naphthyl ketones. | 2001 Jan 26 |
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Synthesis and in vitro antifungal activity of 1-amino-3,4-dialkylnaphthalene-2-carbonitriles and their analogues. | 2001 Jul |
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No enhancement in bioconcentration of organic contaminants by low levels of DOM. | 2001 Jul |
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Arylisothiocyanate-containing esters of caffeic acid designed as affinity ligands for HIV-1 integrase. | 2001 Jul |
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Effectiveness of an anaerobic granular activated carbon fluidized-bed bioreactor to treat soil wash fluids: a proposed strategy for remediating PCP/PAH contaminated soils. | 2001 Jul |
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Biodegradation of carbaryl by a Micrococcus species. | 2001 Jul |
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Biodegradation of non-desorbable naphthalene in soils. | 2001 Jul 1 |
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Marinobacter strain NCE312 has a Pseudomonas-like naphthalene dioxygenase. | 2001 Jul 10 |
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Corannulene as a Lewis base: computational modeling of protonation and lithium cation binding. | 2001 Jul 11 |
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Highly potent growth hormone secretagogues: hybrids of NN703 and ipamorelin. | 2001 Jul 23 |
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Active site characteristics of CYP4B1 probed with aromatic ligands. | 2001 Jul 24 |
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Mutagenicity of electrophilic N-acyloxy-N-alkoxyamides. | 2001 Jul 25 |
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Determination of the electron affinities of alpha- and beta-naphthyl radicals using the kinetic method with full entropy analysis. The C-H bond dissociation energies of naphthalene. | 2001 Jun |
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Synthesis of potential aldose reductase inhibitors based on minimal pharmacophore requirements. | 2001 Jun |
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Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. | 2001 Jun |
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Toxicity tests to assess pollutants removal during wastewater treatment and the quality of receiving waters in Argentina. | 2001 Jun |
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Removal of naphthalene, phenanthrene, and pyrene by sorbents from hot gas. | 2001 Jun 1 |
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Inhaled naphthalene causes dose dependent Clara cell cytotoxicity in mice but not in rats. | 2001 Jun 1 |
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Determination of absolute configuration using vibrational circular dichroism spectroscopy: the chiral sulfoxide 1-(2-methylnaphthyl) methyl sulfoxide. | 2001 Jun 1 |
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A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes. | 2001 Jun 15 |
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Enhancing reductive cleavage of aromatic carboxamides. | 2001 Jun 28 |
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2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. | 2001 Jun 7 |
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Characterization of volatile organic compounds in smoke at experimental fires. | 2001 Jun 8 |
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The Aspergillus nidulans pyrG89 mutation alters glycosylation of secreted acid phosphatase. | 2001 Mar |
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Polycyclic aromatic hydrocarbons (PAHs) in indoor and outdoor air of Hangzhou, China. | 2001 Mar 1 |
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Numerical simulation of the infrared emission of interstellar dust. | 2001 Mar 15 |
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Mass/heat transfer in dimpled two-pass coolant passages with rotation. | 2001 May |
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Determination of photophysical rate constants for the non-protected fluid room temperature phosphorescence of several naphthalene derivatives. | 2001 May |
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Efficiency of naphthalene and salicylate degradation by a recombinant Pseudomonas putida mutant strain defective in glucose metabolism. | 2001 May |
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High-rate 3-methylcatechol production in Pseudomonas putida strains by means of a novel expression system. | 2001 May |
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Ambient air quality at the site of a former manufactured gas plant. | 2001 May |
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Constitutive and inducible hydroxylase activities involved in the degradation of naphthalene by Cunninghamella elegans. | 2001 May |
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Two new chlorinated naphthalene glycosides from Rumex patientia. | 2001 May |
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Photochemistry of 2-hydroxy-4-trifluoromethylbenzoic acid, major metabolite of the photosensitizing platelet antiaggregant drug triflusal. | 2001 May |
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Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants. | 2001 May 22 |
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Convergent synthesis of potent peptide inhibitors of the Grb2-SH2 domain by palladium catalyzed coupling of a terminal alkyne. | 2001 May 7 |
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Determination of trace levels of manganese in various biological and environmental samples by atomic absorption spectrometry after solid-liquid extraction and preconcentration with the ion pair formed by the nitroso-S anion and the tetradecyldimethylbenzylammonium cation. | 2001 May-Jun |
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Use of selective inhibitors and chromogenic substrates to differentiate bacteria based on toluene oxygenase activity. | 2001 Sep |
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C45188
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EPA PESTICIDE CODE |
55801
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2166IN72UN
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DTXSID8020913
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2166IN72UN
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SUB128902
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C29839
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184
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m7725
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37565
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931
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1457083
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91-20-3
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NAPHTHALENE
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202-049-5
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C031721
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naphthalene
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100000174863
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ACTIVE MOIETY
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