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Details

Stereochemistry ACHIRAL
Molecular Formula C10H8
Molecular Weight 128.1705
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NAPHTHALENE

SMILES

C1=CC2=C(C=C1)C=CC=C2

InChI

InChIKey=UFWIBTONFRDIAS-UHFFFAOYSA-N
InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H

HIDE SMILES / InChI

Description

Naphthalene is a crystalline aromatic hydrocarbon usually obtained by distillation of coal tar. Once used as a moth repellent, it is now important as a reactant in the production of phthalic anhydride, which in turn is used for making plasticizers, alkyd resins, and polyester resins. Other fumigant uses of naphthalene include use in soil as a fumigant pesticide, and in attic spaces to repel animals. In the past, naphthalene was administered orally to kill parasitic worms in livestock. In humans, exposure to large amounts of naphthalene may damage or destroy red blood cells. Humans, particularly children, have developed this condition after ingesting mothballs or deodorant blocks containing naphthalene. Some of the symptoms of naphthalene poisoning are fatigue, lack of appetite, restlessness, and pale skin. Exposure to large amounts of naphthalene may also cause nausea, vomiting, diarrhea, blood in the urine, and jaundice (yellow coloration of the skin).

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
EQUIOPATHICS WRM CLEAR
Palliative
ALLERGIES
Palliative
NAPHTHALINUM

PubMed

Sample Use Guides

In Vivo Use Guide
Take 4 or 6 Pellets by mouth, three times daily
Route of Administration: Oral
In Vitro Use Guide
At the 0.10, 0.1 and 0.5 of LD(50) dose (316 mg/kg), the Naphthalene induced increases of 1.8- to 3. 9-fold in brain and liver tissue DNA fragmentation.