1-NAPHTHOL

Possibly Marketed Outside US

First approved in 2016

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H8O
Molecular Weight	144.1699
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=C2C=CC=CC2=CC=C1

InChI

InChIKey=KJCVRFUGPWSIIH-UHFFFAOYSA-N

InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H

HIDE SMILES / InChI

Molecular Formula	C10H8O
Molecular Weight	144.1699
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
[Determination of T lymphocytes and trace elements in spleen from rats infected with Toxoplasma gondii].	2001	12572072
Cooxidation of naphthalene and other polycyclic aromatic hydrocarbons by the nitrifying bacterium, Nitrosomonas europaea.	2002	12713129
Biotransformation of naphthalene and diaryl ethers by green microalgae.	2002	12521287
Resistance of aphis gossypii (Homoptera: Aphididae) to fenvalerate and imidacloprid and activities of detoxification enzymes on cotton and cucumber.	2002 Apr	12020021
Rabbit serum albumin hydrolyzes the carbamate carbaryl.	2002 Apr	11952338
Effect of weaning on small intestinal structure and function in the piglet.	2002 Aug	12462912
4-Aryloxybutenolides as "chiral aldehyde" equivalents: an efficient enantioselective synthesis of (+)-brefeldin a.	2002 Aug 14	12167000
Continuous monitoring of prostatic acid phosphatase using self-indicating substrates.	2002 Dec	12417098
Thin-layer chromatography and electrospray mass spectrometry coupled using a surface sampling probe.	2002 Dec 15	12510741
Detoxication mechanism of exogenous monatomic phenols in pea seedlings.	2002 Feb	11886181
Quantification of monohydroxy-PAH metabolites in urine by solid-phase extraction with isotope dilution-GC-MS.	2002 Jan	11939197
Catalytic asymmetric oxidative couplings of 2-naphthols by tridentate N-ketopinidene-based vanadyl dicarboxylates.	2002 Jul 25	12123368
Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.	2002 Jun 15	12051676
Optimization of catalyst enantioselectivity and activity using achiral and meso ligands.	2002 Jun 19	12059216
Diastereo- and enantioselective carbolithiation of allyl o-lithioaryl ethers. New chiral cyclopropane derivatives.	2002 Jun 27	12074673
Determination of 4-aminophenol using the quartz crystal microbalance sensor.	2002 Mar	11996361
Protease-mediated fragmentation of p-amidobenzyl ethers: a new strategy for the activation of anticancer prodrugs.	2002 Mar 22	11895404
An enzymatic method for removal of phenol from industrial effluent.	2002 May	12071643
Histologic characteristics and local cellular immunity of the gland of the third eyelid after topical ophthalmic administration of 2% cyclosporine for treatment of dogs with keratoconjunctivitis sicca.	2002 May	12013470
A chiral molecular square with metallo-corners for enantioselective sensing.	2002 May 1	11971690
Canine sulfotransferase SULT1A1: molecular cloning, expression, and characterization.	2002 May 15	12054462
Apoptosis control and proliferation marker in human normal and neoplastic adrenocortical tissues.	2002 May 20	12085205
Synthesis of novel BINOL-derived chiral bisphosphorus ligands and their application in catalytic asymmetric hydrogenation.	2002 May 21	12122696
Stable expression of rat sulfotransferase 1B1 in V79 cells: activation of benzylic alcohols to mutagens.	2002 Nov	12419836
Synthesis of hexagonal and cubic super-microporous niobium phosphates with anion exchange capacity and catalytic properties.	2002 Nov 21	12510307
Dual enzyme electrochemical coding for detecting DNA hybridization.	2002 Oct	12430595
Detection of hantavirus infection in hemolyzed mouse blood using alkaline phosphatase conjugate.	2002 Oct	12243909
Determination of selected monohydroxy metabolites of 2-, 3- and 4-ring polycyclic aromatic hydrocarbons in urine by solid-phase microextraction and isotope dilution gas chromatography-mass spectrometry.	2002 Oct 5	12376123
Gold bands as a suitable surface for enzyme immunoassays.	2002 Sep	12191928
Diastereoisomeric singly bridged cyclophosphazene-macrocyclic compounds.	2002 Sep 23	12230399
Insight into the mechanism of the asymmetric addition of alkyl groups to aldehydes catalyzed by titanium-BINOLate species.	2002 Sep 4	12197736
Synthesis and local anaesthetic activity of 2-substituted-N-(2-diethylaminoethyl)-acetamides.	2003	12608012
Simultaneous analysis of naphthols, phenanthrols, and 1-hydroxypyrene in urine as biomarkers of polycyclic aromatic hydrocarbon exposure: intraindividual variance in the urinary metabolite excretion profiles caused by intervention with beta-naphthoflavone induction in the rat.	2003 Apr	12698233
Novel poly (vinyl chloride) matrix membrane electrodes for the determination of phenolic pollutants in waste water.	2003 Apr	12697221
Induction of T(4) UDP-GT activity, serum thyroid stimulating hormone, and thyroid follicular cell proliferation in mice treated with microsomal enzyme inducers.	2003 Apr 1	12668117
anti-Selective direct catalytic asymmetric Mannich-type reaction of hydroxyketone providing beta-amino alcohols.	2003 Apr 23	12696881
A phylogenetic comparison between acute monocytic leukemia cells and monocytes-macrophages in lower vertebrates.	2003 Feb	12675202
(2-Naphthoxy)acetyl chloride, a simple fluorescent reagent.	2003 Feb 14	12613813
Solid-phase microextraction from small volumes of sample in a glass capillary.	2003 Feb 21	12647818
Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme.	2003 Feb 7	12435745
Xenobiotic conjugation systems in deer compared with cattle and rat.	2003 Jan	12524029
Catalytic activities of cytochrome P450 enzymes and UDP-glucuronosyltransferases involved in drug metabolism in rat everted sacs and intestinal microsomes.	2003 Jan	12519693
[Environmental and biological reference values of aromatic polycyclic hydrocarbons].	2003 Jan-Mar	12696489
Functional changes and motility characteristics of Japanese Black bull spermatozoa separated by Percoll.	2003 Jul 15	12695052
The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases.	2003 Jun	12756209
Amperometric biosensors based on recombinant laccases for phenols determination.	2003 Mar	12485779
Catalysis of the Michael addition reaction by late transition metal complexes of BINOL-derived salens.	2003 Mar 7	12608819
The oxygenase component of phenol hydroxylase from Acinetobacter radioresistens S13.	2003 May	12752444
Biodegradation of phenanthrene by Pseudomonas sp. strain PP2: novel metabolic pathway, role of biosurfactant and cell surface hydrophobicity in hydrocarbon assimilation.	2003 May	12743764
Optical biosensor for simultaneous detection of captan and organophosphorus compounds.	2003 May	12706567

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 04:30:39 GMT 2023` Edited by `admin` on `Sat Dec 16 04:30:39 GMT 2023`
Record UNII	2A71EAQ389
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-NAPHTHOL

Official Name

English

DULOXETINE IMPURITY D [USP IMPURITY]

Common Name

English

.ALPHA.-NAPHTHOL

Systematic Name

English

1-NAPHTHALENOL

Systematic Name

English

1-NAPHTHOL [INCI]

Common Name

English

ALPHA-NAPHTHOL

Systematic Name

English

NSC-9586

Code

English

1-HYDROXYNAPHTHALENE

Systematic Name

English

NAPHTHALEN-1-OL

Systematic Name

English

1-NAPHTOL-

Common Name

English

DULOXETINE IMPURITY D

Common Name

English

1-NAPHTHOL [MI]

Common Name

English

NAPHTHOL, 1-

Systematic Name

English

1-NAPHTHOL [HSDB]

Common Name

English

DULOXETINE HYDROCHLORIDE IMPURITY D [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

206500