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Search results for rosuvastatin in Related Substance Name (approximate match)

Showing 1 - 10 of 21 results

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ROSUVASTATIN

413KH5ZJ73

Search for Structure

Status:

US Approved Rx (2016)

Source:

ANDA079169

(2016)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=079169

First approved in 2003

Source:

NDA021366

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021366

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Hypertriglyceridemia

Dysbetalipoproteinemia

Hypercholesterolemia

Atherosclerosis

CRESTOR (rosuvastatin calcium) is an inhibitor of HMG-CoA reductase. It has been widely launched for the treatment of patients with dyslipidaemia and has also been approved in the US and EU to slow the progression of atherosclerosis.

ZINC CATION

13S1S8SF37

Search for Structure

Status:

US Approved OTC

Source:

21 CFR 347.10(t) skin protectant zinc carbonate

Source URL:

https://www.gpo.gov/fdsys/pkg/CFR-2018-title21-vol5/xml/CFR-2018-title21-vol5-sec347-10.xml

First marketed in 1921

Source:

Precipitated Zinc Carbonate U.S.P.

Source URL:

https://www.gutenberg.org/files/41778/41778-h/41778-h.htm

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Streptococcus mutans

respiratory burst

transformed cell apoptotic process

ultraviolet B-induced damage

T cell mediated immunity

Zinc transporter ZIP1

Zinc transporter ZIP2

Conditions:

Ulcerative colitis

Acute myeloid leukemia

Poison Ivy dermatitis

Diaper dermatitis

Gastrointestinal disorders

Renal insufficiency

Zinc deficiency

Zinc monocarbonate (Zinc Carbonate) is an inorganic salt. In the United States, Zinc Carbonate may be used as an active ingredient in OTC drug products. When used as an active drug ingredient, the established name is Zinc Carbonate. Zinc monocarbonate is generally recognized as safe by FDA. It is used as skin protectant active ingredient. Zinc carbonate was found to retard the degradation of some poly(lactide-co-glycolide) (PLG) microspheres in vivo and in vitro. Adding Zinc Carbonate is essential during the preparation of PLGA microspheres. It can remarkably improve the stability of drugs in the acid microenvironment inside PLGA microspheres.

(3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-(((2-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)-2-HYDROXYETHYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

7DWS9BK2LZ

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (EPIMERIC)

(3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-((((E)-2-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)ETHENYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

QFH4RFG7WF

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

(3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-(((2-HYDROXY-2-METHYLPROPYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

6HU79XG7AR

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Calcium (3R,5S,E)-7-(4-(4-fluorophenyl)-2-{2-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl]-2-hydroxy-N-methylethylsulfonamido}-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate salt (1:2)

Q3X3NV27UE

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (MIXED)

(3R,6E)-7-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)-3-HYDROXY-5-OXOHEPT-6-ENOIC ACID

1A3WU50C5Q

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

(3S,5R,6E)-7-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)-5-PYRIMIDINYL)-3,5-DIHYDROXY-6-HEPTENOIC ACID

GED87J49TB

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

TERT-BUTYL 2-((4R,6S)-6-((E)-2-(4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLMETHYLSULFONAMIDO)PYRIMIDIN-5-YL)VINYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE

10S8DBZ6MG

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

ROSUVASTATIN LACTONE

FL37W41F3T

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

Structure of ROSUVASTATIN

ABSOLUTE

Structure of ZINC CATION

ACHIRAL

Structure of (3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-(((2-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)-2-HYDROXYETHYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

EPIMERIC

(3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-(((2-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)-2-HYDROXYETHYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

Structure of (3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-((((E)-2-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)ETHENYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

ABSOLUTE

(3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-((((E)-2-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)ETHENYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

Structure of (3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-(((2-HYDROXY-2-METHYLPROPYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

ABSOLUTE

(3R,5S,6E)-7-(4-(4-FLUOROPHENYL)-2-(((2-HYDROXY-2-METHYLPROPYL)SULFONYL)(METHYL)AMINO)-6-(1-METHYLETHYL)PYRIMIDIN-5-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

Structure of Calcium (3R,5S,E)-7-(4-(4-fluorophenyl)-2-{2-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl]-2-hydroxy-N-methylethylsulfonamido}-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate salt (1:2)

MIXED

Calcium (3R,5S,E)-7-(4-(4-fluorophenyl)-2-{2-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl]-2-hydroxy-N-methylethylsulfonamido}-6-isopropylpyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate salt (1:2)

Structure of (3R,6E)-7-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)-3-HYDROXY-5-OXOHEPT-6-ENOIC ACID

ABSOLUTE

(3R,6E)-7-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)PYRIMIDIN-5-YL)-3-HYDROXY-5-OXOHEPT-6-ENOIC ACID

Structure of (3S,5R,6E)-7-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)-5-PYRIMIDINYL)-3,5-DIHYDROXY-6-HEPTENOIC ACID

ABSOLUTE

(3S,5R,6E)-7-(4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-(METHYL(METHYLSULFONYL)AMINO)-5-PYRIMIDINYL)-3,5-DIHYDROXY-6-HEPTENOIC ACID

Structure of TERT-BUTYL 2-((4R,6S)-6-((E)-2-(4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLMETHYLSULFONAMIDO)PYRIMIDIN-5-YL)VINYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE

ACHIRAL

TERT-BUTYL 2-((4R,6S)-6-((E)-2-(4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLMETHYLSULFONAMIDO)PYRIMIDIN-5-YL)VINYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE

Structure of ROSUVASTATIN LACTONE

ABSOLUTE

ROSUVASTATIN LACTONE

Showing 1 - 10 of 21 results

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