Inxight Drugs

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Return Home Inxight Drugs

Home
Browse Drugs
Search
- Structure Search
- Sequence Search
Downloads
About

Show Filters

Hide Filters

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

{{facet.display}}

{{facet.count}}

{{facet.count}}

All Match

Any Match

Exclude Selected

Exclude Selected

Search results for naloxegol in Related Substance Name (approximate match)

Showing 1 - 10 of 12 results

First page disabled
Previous page disabled
1
Next page
Next page

NALOXEGOL

44T7335BKE

Search for Structure

Status:

US Approved Rx (2014)

Source:

NDA204760

(2014)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=204760

First approved in 2014

Source:

NDA204760

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=204760

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

Mu-type opioid receptor

Conditions:

Opioid-induced constipation

MOVANTIK (naloxegol) is a peripherally-acting mu-opioid receptor antagonist indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic noncancer pain. It is being investigated for the treatment of constipation as a side effect of prescription opioid pain medicines.

HO-PEG5-NALOXOL

UN8DF3ZPX5

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

3,6,9,12-TETRAOXATETRADECANOIC ACID, 14-(((5.ALPHA.,6.ALPHA.)-4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPEN-1-YL)MORPHINAN-6-YL)OXY)-

V475ZW9MQR

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

ACETIC ACID, 2-(2-(2-(2-(((5.ALPHA.,6.ALPHA.)-4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPEN-1-YL)MORPHINAN-6-YL)OXY)ETHOXY)ETHOXY)ETHOXY)-

2ZU68V975P

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

CARBOXYMETHYL-PEG6-NALOXOL

SVN3WC4C23

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

PLASMA PROTEIN FRACTION (HUMAN)

6D53G0FD0Z

Status:

US Approved Rx (2013)

Source:

BLA125416

(2013)

Source URL:

https://www.fda.gov/media/113210/download

First approved in 1958

Source:

BLA101140

Source URL:

https://www.fda.gov/media/113210/download

Class:

MIXTURE

CYTOCHROME P450 2D6

8E4LAA4357

Subunit 1 (497) Similarity Search

Sequence Search

Subunit 1 (497) Similarity Search

Status:

Investigational

Source:

NCT03534063: Not Applicable Interventional Completed Pain, Postoperative

(2018)

Source URL:

https://clinicaltrials.gov/ct2/show/NCT03534063

Class:

PROTEIN

MU-TYPE OPIOID RECEPTOR

1PE72K8X46

Subunit 1 (400) Similarity Search

Sequence Search

Subunit 1 (400) Similarity Search

Status:

Other

Class:

PROTEIN

CYTOCHROME P450 3A4

PUO0521HZV

Subunit 1 (502) Similarity Search

Sequence Search

Subunit 1 (502) Similarity Search

Status:

Other

Class:

PROTEIN

MULTIDRUG RESISTANCE PROTEIN 1

22ES734693

Subunit 1 (1280) Similarity Search

Sequence Search

Subunit 1 (1280) Similarity Search

Status:

Other

Class:

PROTEIN

Structure of NALOXEGOL

ABSOLUTE

Structure of HO-PEG5-NALOXOL

ABSOLUTE

HO-PEG5-NALOXOL

Structure of 3,6,9,12-TETRAOXATETRADECANOIC ACID, 14-(((5.ALPHA.,6.ALPHA.)-4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPEN-1-YL)MORPHINAN-6-YL)OXY)-

ABSOLUTE

3,6,9,12-TETRAOXATETRADECANOIC ACID, 14-(((5.ALPHA.,6.ALPHA.)-4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPEN-1-YL)MORPHINAN-6-YL)OXY)-

Structure of ACETIC ACID, 2-(2-(2-(2-(((5.ALPHA.,6.ALPHA.)-4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPEN-1-YL)MORPHINAN-6-YL)OXY)ETHOXY)ETHOXY)ETHOXY)-

ABSOLUTE

ACETIC ACID, 2-(2-(2-(2-(((5.ALPHA.,6.ALPHA.)-4,5-EPOXY-3,14-DIHYDROXY-17-(2-PROPEN-1-YL)MORPHINAN-6-YL)OXY)ETHOXY)ETHOXY)ETHOXY)-

Structure of CARBOXYMETHYL-PEG6-NALOXOL

ABSOLUTE

CARBOXYMETHYL-PEG6-NALOXOL

6D53G0FD0Z
Not a public record

Mixture

PLASMA PROTEIN FRACTION (HUMAN)

Protein

CYTOCHROME P450 2D6

Protein

MU-TYPE OPIOID RECEPTOR

Protein

CYTOCHROME P450 3A4

Protein

MULTIDRUG RESISTANCE PROTEIN 1

Showing 1 - 10 of 12 results

First page disabled
Previous page disabled
1
Next page
Next page

HHS VULNERABILITY DISCLOSURE

For language access assistance, contact the NCATS Public Information Officer

National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966


			version 1.1