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Search results for lansoprazole in Related Substance Name (approximate match)
Status:
US Approved Rx
(2012)
Source:
ANDA202176
(2012)
Source URL:
First approved in 1995
Source:
NDA020406
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Levolansoprazole is the levorotary (L-enantiomer) form of proton-pump inhibitor (PPI) Lansoprazole. Lansoprazole is a racemic 1:1 mixture of the enantiomers dexlansoprazole (Dexilant, formerly named Kapidex) and Levolansoprazole. Lansoprazole has used to the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastrointestinal bleeds with NSAID use. Levolansoprazole is extensively metabolized in the liver. Two metabolites have been identified in measurable quantities in plasma (the hydroxylated sulfinyl and sulfone derivatives of Levolansoprazole).