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Details

Stereochemistry ACHIRAL
Molecular Formula C7H6N2S
Molecular Weight 150.201
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-BENZIMIDAZOLETHIOL

SMILES

SC1=NC2=C(N1)C=CC=C2

InChI

InChIKey=YHMYGUUIMTVXNW-UHFFFAOYSA-N
InChI=1S/C7H6N2S/c10-7-8-5-3-1-2-4-6(5)9-7/h1-4H,(H2,8,9,10)

HIDE SMILES / InChI
Molecular Formula C7H6N2S
Molecular Weight 150.201
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Synthesis and controlled hydrolysis of organolanthanide complexes with mono- and dianionic benzimidazole-2-thiolate ligands.
2010-12-07
Inhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening.
2010-12-03
3-[2-(1H-Benzimidazol-2-ylsulfan-yl)eth-yl]-1,3-oxazolidin-2-one.
2010-11-13
Revisit to the reaction of o-phenylene diamine with thiosemicarbazide to give benzimidazole-2-thione rather than benzotriazine-2-thione and its glycosylation.
2010-09
Ratiometric surface enhanced Raman quantification of ligand adsorption onto a gold nanoparticle.
2010-07-01
Novel benzo[d]imidazole-2(3H)-thiones as potent inhibitors of the alpha-melanocyte stimulating hormone induced melanogenesis in melanoma B16 cells.
2010-07
[Antiarrhythmic properties of afobazole and other 2-mercaptobensimidazole derivatives].
2010-05
Derivatives of benzimidazole pharmacophore: synthesis, anticonvulsant, antidiabetic and DNA cleavage studies.
2010-05
1,3-Bis(ethoxy-meth-yl)-1H-benzimidazole-2(3H)-thione.
2010-04-24
Simultaneous spectrophotometric determination of 2-thiouracil and 2-mercaptobenzimidazole in animal tissue using multivariate calibration methods: concerns and rapid methods for detection.
2010-03
Structural motifs and biological studies of new antimony(III) iodide complexes with thiones.
2010-01-18
[Effectiveness of combined application of ursosan and anxiolytic 2-mercaptobenzimidazole in early stage of cholelithiasis].
2010
Application of natural and modified hectorite clays as adsorbents to removal of Cr(VI) from aqueous solution--thermodynamic and equilibrium study.
2009-12-15
Determination of thyreostats in urine and thyroid gland by ultra high performance liquid chromatography tandem mass spectrometry.
2009-11-13
2,2'-Bis(methyl-ene)-3,3'-(2-thioxo-2,3-dihydro-1H-benzimidazole-1,3-di-yl)dipropane-nitrile.
2009-10-31
3-[(1H-Benzimidazol-2-yl)sulfanyl-methyl]benzonitrile.
2009-05-23
A polynuclear d10-d10 metal complex with unusual near-infrared luminescence and high thermal stability.
2009-04-06
[Specific effects of selective anxiolytic afobazole on the cardiovascular system].
2009-04-02
1H-Benzimidazole-2(3H)-thione.
2009-03-14
Structure and properties of binuclear nitrosyl iron complex with benzimidazole-2-thiolyl.
2009-03-14
New antimony(III) bromide complexes with thioamides: synthesis, characterization, and cytostatic properties.
2009-03-02
Determination of mercury in water and fish samples by cold vapor atomic absorption spectrometry after solid phase extraction on agar modified with 2-mercaptobenzimidazole.
2009-01-30
Parallel synthesis of 2-sulphanylated bis-benzimidazoles on soluble polymer support.
2008-04-15
In vivo effects of afobazole (2-mercaptobenzimidazole derivative) on the 7,12-dimethylbenz [alpha]anthracene-induced oncogene and suppressor gene expression.
2008-01-24
Syntheses and biological activities of benzimidazolo[2,1-b] benzo[e]thiazepin-5(10H)-ones.
2008-01
Synthesis, structural characterization, and biological studies of new antimony(III) complexes with thiones. The influence of the solvent on the geometry of the complexes.
2007-10-15
Synthesis, structural characterization and biological study of new organotin(IV), silver(I) and antimony(III) complexes with thioamides.
2007-09-05
Modification of silica gel by attachment of 2-mercaptobenzimidazole for use in removing Hg(II) from aqueous media: a thermodynamic approach.
2007-07-01
Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds.
2007-04
[Synthesis and bioactivity of N- [4- ( benzimidazole-2-thio) phenyl] -N'-alkyl guanidine derivatives].
2007-02
Benzofused tricycles based on 2-quinoxalinol.
2007-01-09
The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties.
2007
A novel approach for simultaneous determination of 2-mercaptobenzimidazole and derivatives of 2-thiouracil in animal tissue by gas chromatography/mass spectrometry.
2007
Green route for the heterocyclization of 2-mercaptobenzimidazole into beta-lactum segment derivatives containing -CONH- bridge with benzimidazole: Screening in vitro antimicrobial activity with various microorganisms.
2006-12-15
Respective contributions of polar vs enthalpy effects in the addition/fragmentation of mercaptobenzoxazole-derived thiyl radicals and analogues to double bonds.
2006-10-19
Experimental and density functional theory study of the vibrational properties of 2-mercaptobenzimidazole in interaction with gold.
2006-10-05
An analytical method to screen for six thyreostatic drug residues in the thyroid gland and muscle tissues of food producing animals by liquid chromatography with ultraviolet absorption detection and liquid chromatography/mass spectrometry.
2006-04-28
Pressure-tuning Raman spectra of diiodine thioamide compounds: models for antithyroid drug activity.
2006
Interaction of thioamides, selenoamides, and amides with diiodine.
2006
Reactions Between Chalcogen Donors and Dihalogens/Interalogens: Typology of Products and Their Characterization by FT-Raman Spectroscopy.
2006
Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions.
2006
Synthesis, structural characterization, and computational studies of novel diiodine adducts with the heterocyclic thioamides N-methylbenzothiazole-2-thione and benzimidazole-2-thione: implications with the mechanism of action of antithyroid drugs.
2005-11-14
Synthesis, antibacterial, antifungal activity and interaction of CT-DNA with a new benzimidazole derived Cu(II) complex.
2005-11
Domino Michael addition-carbene rearrangement-cyclization reaction of 1-alkynyl(aryl)-lambda3-bromanes with 2-mercapto-1,3-benzazoles.
2005-10-28
[A comparative study of the effect of brazidole, amiodarone, sotalol, and hydroxyzine on potassium ionic channels of mollusks neurons].
2005-10-01
Prediction of genotoxicity of chemical compounds by statistical learning methods.
2005-06
High-throughput microplate phosphorylation assays based on DevR-DevS/Rv2027c 2-component signal transduction pathway to screen for novel antitubercular compounds.
2005-04
New route to 3-alkylthiazolo[3,2-a]benzimidazole derivatives.
2005-02-28
Determination of very low levels of dissolved mercury(II) and methylmercury in river waters by continuous flow with on-line UV decomposition and cold-vapor atomic fluorescence spectrometry after pre-concentration on a silica gel-2-mercaptobenzimidazol sorbent.
2001-12-24
Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure.
1993-07
Patents

Patents

04873237
1
05683989
7
05998456
1
06043373
2
06787561
2
06906078
3
07803790
2
JP2000154472A
1
JP2006347989A
3
JPH01315440A
1
JPH02219815A
1
JPH07196868A
1
JPH0762232A
1
JPH09169873A
1
JPH0952987A
1
JPH095996A
1
JPH09875A
1
JPH10158433A
1
JPH10292261A
2
JPH10338787A
2
JPH1073718A
1
JPH11269336A
1
JPH1143517A
1
JPS5232046A
1
JPS5392720A
1
JPS5448764A
1
JPS55104335A
1
JPS5673086A
1
JPS5695162A
1
JPS57162738A
1
JPS58122943A
1
JPS588738A
1
JPS59226002A
1
JPS61163986A
1
JPS61228043A
1
JPS62190201A
1
JPS62212444A
1
JPS6241266A
1
JPS6389517A
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:12:21 GMT 2025
Edited
by admin
on Mon Mar 31 19:12:21 GMT 2025
Record UNII
619CVM6HOK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2-BENZIMIDAZOLETHIOL
MI  
Systematic Name English
RABEPRAZOLE RELATED COMPOUND C
USP-RS  
Preferred Name English
NSC-21414
Code English
MERCAPTOBENZIMIDAZOLE [USP IMPURITY]
Common Name English
MERCAPTOBENZIMIDAZOLE
Common Name English
2-MERCAPTOBENZIMIDAZOLE
Systematic Name English
MERCAPTOBENZIMIDAZOLE, 2-
Systematic Name English
NSC-186246
Code English
RABEPRAZOLE RELATED COMPOUND C [USP IMPURITY]
Common Name English
RABEPRAZOLE SODIUM IMPURITY F [EP IMPURITY]
Common Name English
NCI-C60980
Code English
1H-BENZIMIDAZOLE-2-THIOL
Systematic Name English
2-BENZIMIDAZOLETHIOL [MI]
Common Name English
RABEPRAZOLE RELATED COMPOUND C [USP-RS]
Common Name English
2H-BENZIMIDAZOLE-2-THIONE, 1,3-DIHYDRO-
Systematic Name English
NCI-C56268
Code English
LANSOPRAZOLE IMPURITY E [EP IMPURITY]
Common Name English
1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-THIONE
Systematic Name English
Code System Code Type Description
WIKIPEDIA
Mercaptobenzimidazole
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
MESH
C030698
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
PUBCHEM
707035
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
MERCK INDEX
m2354
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY Merck Index
NSC
186246
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
NSC
21414
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
ECHA (EC/EINECS)
209-502-6
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
SMS_ID
300000052996
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
FDA UNII
619CVM6HOK
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
CAS
134469-07-1
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
ALTERNATIVE
RS_ITEM_NUM
1598042
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
CAS
583-39-1
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
EPA CompTox
DTXSID9025536
Created by admin on Mon Mar 31 19:12:22 GMT 2025 , Edited by admin on Mon Mar 31 19:12:22 GMT 2025
PRIMARY
Related Record Type Details
ZINC 2-MERCAPTOTOLUIMIDAZOLE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of LANSOPRAZOLE
PARENT -> IMPURITY
Structure of RABEPRAZOLE SODIUM
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of RABEPRAZOLE SODIUM
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
NIH
NCATS
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