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Search results for "rucaparib" in Related Substance Name (exact match)

Showing 1 - 10 of 21 results

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RUCAPARIB

8237F3U7EH

Search for Structure

Status:

US Approved Rx (2016)

Source:

NDA209115

(2016)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=209115

First approved in 2016

Source:

NDA209115

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=209115

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

PARP 1, 2 and 3

Conditions:

Castrate-resistant prostate cancer

Rucaparib is a poly (ADP-ribose) polymerase (PARP) inhibitor indicated for the treatment of advanced mutant BRCA ovarian cancer. Rucaparib is being investigated in clinical trials against prostate cancer, breast cancer and other neoplasms.

4-(8-FLUORO-6-METHYL-1-OXO-2,3,4,6-TETRAHYDRO-1H-AZEPINO(5,4,3-CD)INDOL-5-YL)BENZOIC ACID

D57RNL9EV6

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

N-(4-(8-FLUORO-1-OXO-2,3,4,6-TETRAHYDRO-1H-AZEPINO(5,4,3-CD)INDOL-5-YL)BENZYL)FORMAMIDE

HCF2D2KJ6Y

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

BENZAMIDE, 4-(8-FLUORO-3,4,5,6-TETRAHYDRO-6-OXO-1H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-2-YL)-N-METHYL-

53BKY5NTL7

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

BENZOIC ACID, 4-(8-FLUORO-3,4,5,6-TETRAHYDRO-6-OXO-1H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-2-YL)-

V2GJ2XVK6G

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

6H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-6-ONE, 2-(4-(AMINOMETHYL)PHENYL)-8-FLUORO-1,3,4,5-TETRAHYDRO-

4K3MM9XEJ2

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

PLASMA PROTEIN FRACTION (HUMAN)

6D53G0FD0Z

Status:

Possibly Marketed Outside US

Source:

Octaplasma by Octapharma Pharmazeutika Produktionsges M B H [Canada]

Source URL:

https://www.drugbank.ca/drugs/DB13968

First approved in 2013

Source:

BLA125416

Source URL:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=998415d8-9bbe-e5b8-c3b0-3ba0344faacb

Class:

MIXTURE

CYTOCHROME P450 1A2

VK4SQL11C0

Subunit 1 (514) Similarity Search

Sequence Search

Subunit 1 (514) Similarity Search

Status:

Investigational

Source:

NCT03333824: Phase 1 Interventional Completed Solid Tumours

(2017)

Source URL:

https://clinicaltrials.gov/ct2/show/NCT03333824

Class:

PROTEIN

CYTOCHROME P450 2D6

8E4LAA4357

Subunit 1 (497) Similarity Search

Sequence Search

Subunit 1 (497) Similarity Search

Status:

Investigational

Source:

NCT03534063: Not Applicable Interventional Completed Pain, Postoperative

(2018)

Source URL:

https://clinicaltrials.gov/ct2/show/NCT03534063

Class:

PROTEIN

POLY (ADP-RIBOSE) POLYMERASE 3

15Q2UA3FWG

Subunit 1 (533) Similarity Search

Sequence Search

Subunit 1 (533) Similarity Search

Status:

Other

Class:

PROTEIN

Structure of RUCAPARIB

ACHIRAL

Structure of 4-(8-FLUORO-6-METHYL-1-OXO-2,3,4,6-TETRAHYDRO-1H-AZEPINO(5,4,3-CD)INDOL-5-YL)BENZOIC ACID

ACHIRAL

4-(8-FLUORO-6-METHYL-1-OXO-2,3,4,6-TETRAHYDRO-1H-AZEPINO(5,4,3-CD)INDOL-5-YL)BENZOIC ACID

Structure of N-(4-(8-FLUORO-1-OXO-2,3,4,6-TETRAHYDRO-1H-AZEPINO(5,4,3-CD)INDOL-5-YL)BENZYL)FORMAMIDE

ACHIRAL

N-(4-(8-FLUORO-1-OXO-2,3,4,6-TETRAHYDRO-1H-AZEPINO(5,4,3-CD)INDOL-5-YL)BENZYL)FORMAMIDE

Structure of BENZAMIDE, 4-(8-FLUORO-3,4,5,6-TETRAHYDRO-6-OXO-1H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-2-YL)-N-METHYL-

ACHIRAL

BENZAMIDE, 4-(8-FLUORO-3,4,5,6-TETRAHYDRO-6-OXO-1H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-2-YL)-N-METHYL-

Structure of BENZOIC ACID, 4-(8-FLUORO-3,4,5,6-TETRAHYDRO-6-OXO-1H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-2-YL)-

ACHIRAL

BENZOIC ACID, 4-(8-FLUORO-3,4,5,6-TETRAHYDRO-6-OXO-1H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-2-YL)-

Structure of 6H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-6-ONE, 2-(4-(AMINOMETHYL)PHENYL)-8-FLUORO-1,3,4,5-TETRAHYDRO-

ACHIRAL

6H-PYRROLO(4,3,2-EF)(2)BENZAZEPIN-6-ONE, 2-(4-(AMINOMETHYL)PHENYL)-8-FLUORO-1,3,4,5-TETRAHYDRO-

Mixture

PLASMA PROTEIN FRACTION (HUMAN)

Protein

CYTOCHROME P450 1A2

Protein

CYTOCHROME P450 2D6

Protein

POLY (ADP-RIBOSE) POLYMERASE 3

Showing 1 - 10 of 21 results

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