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Restrict the search for
pirfenidone
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There is one exact (name or code) match for pirfenidone
Status:
US Approved Rx
(2017)
Source:
NDA208780
(2017)
Source URL:
First approved in 2014
Source:
NDA022535
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Pirfenidone is a synthetic antifibrotic agent indicated for the treatment of idiopathic pulmonary fibrosis as Esbriet. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors. It also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis. Pirfenidone has demonstrated activity in multiple fibrotic conditions however the exact mechanism of action of pirfenidone in the treatment of IPF has not been established.
Showing 1 - 5 of 5 results
Status:
US Approved Rx
(2017)
Source:
NDA208780
(2017)
Source URL:
First approved in 2014
Source:
NDA022535
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Pirfenidone is a synthetic antifibrotic agent indicated for the treatment of idiopathic pulmonary fibrosis as Esbriet. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors. It also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis. Pirfenidone has demonstrated activity in multiple fibrotic conditions however the exact mechanism of action of pirfenidone in the treatment of IPF has not been established.
Status:
Investigational
Source:
INN:deupirfenidone [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
Octaplasma by Octapharma Pharmazeutika Produktionsges M B H [Canada]
Source URL:
First approved in 2013
Source:
BLA125416
Source URL:
Class:
MIXTURE
Status:
Investigational
Source:
NCT03333824: Phase 1 Interventional Completed Solid Tumours
(2017)
Source URL:
Class:
PROTEIN
