U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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There is one exact (name or code) match for mafodotin

 
Status:
Investigational
Source:
USAN:MAFODOTIN [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Mafodotin (mc-MMAF) is a hydrophilic non-cleavable antimicrotubule and antimitotic agent, monomethyl auristatin F (MMAF) derivative, having a maleimidocaproyl linker (mc linker), which is ready to conjugate to an antibody or other proteins or biopolymers. Antibody-drug conjugates having mafodotin such as Depatuxizumab mafodotin and Belantamab mafodotin have undergone clinical trials for the treatment of neoplasms.

Showing 1 - 10 of 18 results

Status:
Investigational
Source:
USAN:MAFODOTIN [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Mafodotin (mc-MMAF) is a hydrophilic non-cleavable antimicrotubule and antimitotic agent, monomethyl auristatin F (MMAF) derivative, having a maleimidocaproyl linker (mc linker), which is ready to conjugate to an antibody or other proteins or biopolymers. Antibody-drug conjugates having mafodotin such as Depatuxizumab mafodotin and Belantamab mafodotin have undergone clinical trials for the treatment of neoplasms.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:

Status:
Other

Class (Stereo):
CHEMICAL (EPIMERIC)

Status:
Investigational
Source:
NCT03849651: Phase 2 Interventional Recruiting Acute Lymphoblastic Leukemia (ALL)
(2019)
Source URL:

Class:
PROTEIN

Showing 1 - 10 of 18 results