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elafibranor
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There is one exact (name or code) match for elafibranor
Status:
Investigational
Source:
INN:elafibranor [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α and peroxisome proliferator-activated receptor-δ. GFT505 has an active
metabolite, GFT1007, and both have potent agonist activity
for PPAR-a and to a lesser extent for PPAR-d. Elafibranor improves insulin sensitivity, glucose homeostasis, and lipid metabolism and reduces inflammation. Elafibranor (GFT505) reverses nonalcoholic steatohepatitis (NASH) to prevent fibrosis progression. With an outstanding safety and tolerance profile, elafibranor provides NASH patients with needed cardio-protective benefits. Elafibranor is currently being evaluated in the clinical Phase 3 study RESOLVE-IT. The safety profile of GFT505 from the completed clinical
trials appears satisfactory with no indication of PPAR-g agonist
effects such as edema or body weight gain.
Showing 1 - 3 of 3 results
Status:
Investigational
Source:
INN:elafibranor [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α and peroxisome proliferator-activated receptor-δ. GFT505 has an active
metabolite, GFT1007, and both have potent agonist activity
for PPAR-a and to a lesser extent for PPAR-d. Elafibranor improves insulin sensitivity, glucose homeostasis, and lipid metabolism and reduces inflammation. Elafibranor (GFT505) reverses nonalcoholic steatohepatitis (NASH) to prevent fibrosis progression. With an outstanding safety and tolerance profile, elafibranor provides NASH patients with needed cardio-protective benefits. Elafibranor is currently being evaluated in the clinical Phase 3 study RESOLVE-IT. The safety profile of GFT505 from the completed clinical
trials appears satisfactory with no indication of PPAR-g agonist
effects such as edema or body weight gain.
Status:
Investigational
Source:
NCT00374855: Phase 2 Interventional Completed Mild Hypertension
(2006)
Source URL:
Class:
PROTEIN
