Search results for "Pharmacologic Substance[C1909]|Enzyme Inhibitor[C471]|Carbonic Anhydrase Inhibitor" in comments (approximate match)
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Dorzolamide is a sulfonamide and a highly specific carbonic anhydrase II (CA-II) inhibitor, which is the main CA isoenzyme involved in aqueous humor secretion. Dorzolamide is marketed under the trade name Trusopt, indicated in the treatment of elevat...
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory drug that exhibits antiinflammatory, analgesic, and antipyretic activities in animal models. Flurbiprofen Tablets are indicated for relief of the signs and symptoms of rh...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Metha...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Diclorphenamide, a carbonic anhydrase inhibitor, was initially developed for the treatment of glaucome, however, now it is used for patients suffering from primary hypokalemic and hyperkalemic periodic paralysis. The exact mechanism of diclorphenamid...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Acetazolamide, usually sold under the trade name Diamox in some countries. DIAMOX is used for adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery...
Sezolamide (previously known as MK-417), a potent carbonic anhydrase inhibitor capable of reducing intraocular pressure after topical application, was under investigation for the treatment of glaucoma. . Sezolamide is the more potent of the two ster...
Propazolamide is a sulfonamide derivative patented by American Cyanamid Co. useful in the treatment of glaucoma and epilepsy and as oral diuretics. Propazolamide acts as a carbonic anhydrase inhibitor.
Sulfonamide derivative Disulfamide was developed as diuretic agent.
Class (Stereo):
CHEMICAL (ACHIRAL)
Indisulam (also known as E7070) is a sulfonamide derivative patented by Japanese pharmaceutical company Eisai Co. as antitumor agent. Indisulam inhibits cyclin-dependent kinases (CDK), which regulate cell cycle progression and are usually over-expre...