PROPAZOLAMIDE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H8N4O3S2
Molecular Weight	236.272
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PROPAZOLAMIDE

Structure Search

SMILES

CCC(=O)NC1=NN=C(S1)S(N)(=O)=O

InChI

InChIKey=PCBBBQKRWNGNDW-UHFFFAOYSA-N

InChI=1S/C5H8N4O3S2/c1-2-3(10)7-4-8-9-5(13-4)14(6,11)12/h2H2,1H3,(H2,6,11,12)(H,7,8,10)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13411157 | https://www.ncbi.nlm.nih.gov/pubmed/3817035

Propazolamide is a sulfonamide derivative patented by American Cyanamid Co. useful in the treatment of glaucoma and epilepsy and as oral diuretics. Propazolamide acts as a carbonic anhydrase inhibitor.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Acetazolamide-based fungal chitinase inhibitors.	2010-12-01	21044846
Report of a new carbonic anhydrase inhibitor (Squibb-MC-9367).	1957-05	13411157

Patents

Patents

Name

Type

Language

PROPAZOLAMIDE

Official Name

English

propazolamide [INN]

Preferred Name

English

5-PROPIONAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29577

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Code System Code Type Description

FDA UNII

5E2PXL9FZF

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NCI_THESAURUS

C84111

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PUBCHEM

10354098

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EPA CompTox

DTXSID301018994

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ChEMBL

CHEMBL1288786

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INN

482

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CAS

98-75-9

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SMS_ID

100000081152

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EVMPD

SUB10100MIG

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ACTIVE MOIETY


					5E2PXL9FZF