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Showing 1 - 10 of 86 results

Status:
US Approved Rx (2008)
First approved in 2008

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Tapentadol is the first US FDA-approved centrally acting analgesic having both μ-opioid receptor agonist and noradrenaline (norepinephrine) reuptake inhibition activity with minimal serotonin reuptake inhibition. Tapentadol is indicated for the manag...
Status:
US Approved Rx (2020)
First approved in 1996

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid analgesic drug. It is given to patients during surgery to relieve pain and as an adjunct to an anaesthetic. ULTIVA is a µ-opioid agonist with rapid onset and ...
Status:
US Approved Rx (1999)
First approved in 1986

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Alfentanil is an opioid analgesic with a rapid onset of action. Alfentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings...
Status:
US Approved Rx (1995)
First approved in 1984

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Sufentanil is a synthetic opioid analgesic. Sufentanil interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, sufentanil exerts ...
Status:
US Approved Rx (1968)
First approved in 1968

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Fentanyl is a potent agonist of mu opioid receptor. It is used to relieve severe pain, such as after surgery or during cancer treatment, and breakthrough pain (flare-ups of intense pain despite round-the-clock narcotic treatment). Fentanyl is an extr...
Status:
US Approved Rx (2018)
First approved in 1959

Class (Stereo):
CHEMICAL (ABSOLUTE)



Oxymorphone is an analgesic that is FDA approved for the treatment of moderate to severe pain. It is also indicated for relief of anxiety in patients with dyspnea associated with pulmonary edema secondary to acute left ventricular dysfunction. Oxymor...
Status:
US Approved Rx (2021)
First approved in 1953

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Levorphanol, brand name Levo-Dromoran, is an opioid medication used to treat moderate to severe pain. Levorphanol is indicated for the management of moderate to severe pain where an opioid analgesic is appropriate. It is a potent synthetic opioid mu-...
Status:
US Approved Rx (2000)
First approved in 1950

Class (Stereo):
CHEMICAL (ABSOLUTE)



Oxycodone is a semisynthetic opioid used for the management of acute and chronic pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Oxycodone is a highly selective full agonist of the μ-opioid recep...
Status:
US Approved Rx (2018)
First approved in 1947

Class (Stereo):
CHEMICAL (RACEMIC)



Methadone, sold under the brand names Dolophine among others, is an synthetic opioid that is used as the hydrochloride to treat pain and as maintenance therapy or to help with detoxification in people with opioid dependence. Methadone hydrochloride i...
Status:
US Approved Rx (2018)
First approved in 1943

Class (Stereo):
CHEMICAL (ABSOLUTE)


Benzhydrocodone is a prodrug of hydrocodone. Benzhydrocodone is formed by covalently bonding hydrocodone to benzoic acid. Benzhydrocodone itself is not pharmacologically active, but must be metabolized to hydrocodone by enzymes in the intestinal trac...